世界中医药
文章摘要
引用本文:王一荃 王祝鸣 李芸茜 胡晓雯 陈 飞 王凤良 童 华.中药复方金衡灵减轻乳腺癌术后化疗毒副反应的临床观察[J].世界中医药,2012,7(5):.  
中药复方金衡灵减轻乳腺癌术后化疗毒副反应的临床观察
Clinical Observation on Relief of Chemotherapy Side Effects in Postoperative Patients of Breast Cancer by Chinese Herbal Compound Jinhengling
投稿时间:2012-05-30  
DOI:
中文关键词:  乳腺癌  化疗  毒副反应  @ 金衡灵
English Keywords:Breast cancer  Chemotherapy  Side effect  @Jinhengling
基金项目:南京市医学科技发展项目(编号:YKK09092)、南京市科学技术发展计划项目(编号:201001092)
作者单位
王一荃1 王祝鸣2 李芸茜2 胡晓雯2 陈 飞3 王凤良3 童 华3 1 南京中医药大学第一临床医学院江苏省南京市建邺区汉中路155号210046 2 南京医科大学卫生部抗体技术重点实验室 3 南京市妇幼保健院乳腺科 
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中文摘要:
      目的:研究中药复方金衡灵对乳腺癌术后化疗毒副反应的补充治疗作用。方法:将乳腺癌术后均采用TE(多西他赛+表阿霉素)方案化疗的患者分成治疗组和对照组,治疗组、对照组分别服用6个疗程的金衡灵、安慰剂。观察并比较2组患者化疗的毒副反应。结果:化疗后2组脱发、腹泻、口腔炎、感染、过敏、粒缺性发热等发生率均很低,无统计学意义。从化疗第3个疗程开始,治疗组恶心呕吐的发生率明显低于对照组(P<0.05);从第2个疗程开始,治疗组虚弱的发生率明显低于对照组(P<0.05)。结论:中药复方金衡灵在缓解乳腺癌术后化疗毒副反应方面有明显效果,可以提高患者抗病能力和生活质量。
English Summary:
      To observe the effect of Chinese herbal compound Jinhengling on relieving chemotherapy side effects in postoperative patients of breast cancer.Methods:Patients treated with Docetaxel and Epirubicin were divided into two groups. the treatment group were given compound Jinhengling,while the control group were given placebo for six courses.Results:After chemotherapy,the incidence of hair loss,diarrhea,stomatitis,infection,allergies and fever were very low in the two groups. Started from the 3rd course of treatment,the incidence of nausea and vomiting in the treatment group were lower(P<0.05)than in the control group; Started from the 2nd course of treatment,the incidence of weakness in the treatment group was lower(P<0.05)than in the control group.Conclusion:The compound Jinhengling has obvious effect on relieving chemotherapy side effects in postoperative patients of breast cancer,and can improve the immunity and life quality of breast cancer patients.
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