| 引用本文:钟 锐.化浊解毒调肝法联合熊去氧胆酸治疗原发性胆汁性肝硬化30例[J].世界中医药,2012,7(5):. |
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| 化浊解毒调肝法联合熊去氧胆酸治疗原发性胆汁性肝硬化30例 |
| Chinese Medicine Combined with Ursodeoxvcholic Acid for Treatment of Primary Biliary Cirrhosis |
| 投稿时间：2012-06-05 |
| DOI： |
| 中文关键词: 原发性胆汁性肝硬化 中药疗法 血脂 肝功能 |
| English Keywords:Primary biliary cirrhosis Chinese medical therapy Lipid Liver function |
| 基金项目: |
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| 中文摘要: |
| 目的：观察化浊解毒调肝法对原发性胆汁性肝硬化患者的肝功能、血脂的影响。方法：将60例原发性胆汁性肝硬化（PBC）患者随机分为2组。治疗组30例应用熊去氧胆酸加化浊解毒调肝方治疗，对照组应用熊去氧胆酸治疗。2组均1个月为1个疗程，2个疗程后观察临床疗效。结果：治疗组总有效率47%，对照组总有效率31%，2组比较差异有统计学意义（P<0.05），治疗组优于对照组。2组治疗后血脂（CHO、TG）及肝功能（ALB、ALT、GGT、TBil、ALP）较前均有降低，且治疗组下降明显有统计学意义（P<0.05）。结论：化浊解毒调肝法联合熊去氧胆酸对PBC疗效确切，且能降低血脂及肝功能指标，并改善临床症状。 |
| English Summary: |
| To observe effect of Chinese Medicine combined with Ursodeoxvcholic acid (UDCA) on liver functions and lipids of patients with primary biliary cirrhosis. Methods:Sixty patients were randomized to 2 groups, taken respectively Chinese Medicine combined with UDCA, or UDCA only for 2 months. After 2 months, efficacy was compared between the two groups. Results:Total effective rate was 47% of treatment group, compared with 31% of control group (P<0.05). After treatment, patients in both groups had seen lower levels of lipids (CHO、TG) and liver function related parameters (ALB、ALT、GGT、TBil、ALP), improvement was more significant in control group. Conclusion:Chinese Medicine combined with UDCA is effective to treat primary biliary cirrhosis, lower lipid levels and improve liver functions. |
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