| 引用本文:龙 伟 周则卫 张 浩 于光允 姜 明 白佳丽 沈 秀 刘培勋.中药寒热预测系统的建立[J].世界中医药,2013,8(3):. |
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| 中药寒热预测系统的建立 |
| Construction of A Prediction System for Chinese Materia Medica Hot/Cold Properties |
| 投稿时间：2012-06-02 |
| DOI：10.3969/j.issn.1673-7202.2013.03.031 |
| 中文关键词: 中药 药性 寒热 预测 SVM |
| English Keywords:Chinese Materia Medica Properties Hot/cold Prediction SVM |
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| 中文摘要: |
| 中药寒热性质是中药药性的重要特点之一，作者在本文着重介绍了构建的中药寒热性质预测系统，并对中药寒热药性的化学基础进行了探讨。作者建立的寒热预测系统对中药寒热药性的预测准确率，训练集达到833%，测试集达到810%。在此预测模型的基础上，提出了原子数、氢键受体数、电负性表面面积等5个化学描述符，用于解释中药寒热药性的化学基础。 |
| English Summary: |
| Chinese Materia Medica(CMM) properties are characterized as the hot/cold properties, of which we discussed and analyzed chemical fundamentals and our prediction system for CMM was presented particularly. The predictions accuracy of this system are 83.3% and 81% in training and test set respectively. Besides, five descriptors derived from the system such as atomic numbers, the number of H bond acceptors and negative charged surface area, had been put forward to give help on interpretation the relationship between hot/cold properties of CMM and their chemical ingredients. |
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