世界中医药
文章摘要
引用本文:张亚欣 赵进喜 王世东 傅 强 李 景 庞 博.2型糖尿病视网膜病变中医证候学研究[J].世界中医药,2013,8(05):.  
2型糖尿病视网膜病变中医证候学研究
Study on TCM Syndromes and Patterns of Type 2 Diabetes with Retinopathy
投稿时间:2013-04-10  
DOI:10.3969/j.issn.1673-7202.2013.05.006
中文关键词:  分型  糖尿病视网膜病变  糖尿病  眼底改变  中医证候
English Keywords:Patterns classification  Diabetes with retinopathy  Diabetes  Changes of fundi  TCM syndrome
基金项目:
作者单位
张亚欣1 赵进喜1 王世东1 傅 强1 李 景2 庞 博3 1 北京中医药大学东直门医院肾病内分泌科北京100700 2 北京中医医院北京100010 3 中国中医科学院广安门医院北京100053 
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中文摘要:
      目的:本研究针对2型糖尿病视网膜病变开展临床证候学研究,为2型糖尿病视网膜病变临床规范化辨证和治疗提供参考依据。方法:调查北京中医药大学东直门医院肾病内分泌科确诊为2型糖尿病视网膜病变的患者104例,采集信息,录入数据,对资料进行统计学分析。结果:104例DR患者中,证候出现频率:痰湿证>血瘀证>阴虚证>气郁证>湿热证>气虚证出现频率均超过50%,表明此次研究样本在证候分布上正虚以阴虚、气虚为主,标实以痰湿、血瘀、气郁、湿热为主。结论:1)DR病情与患者年龄关系不大,而与DM病程长短呈密切相关性。2)糖尿病肾病、高血压病、高尿酸血症与DR的发生发展关系密切,具有重要的提示意义。3)多证组合、虚实夹杂是DR显著的证候特点。证候演变符合阴虚→气阴两虚→阴阳两虚,阴虚贯穿病变的始终。4)糖化血红蛋白水平与DR痰湿证、湿热证程度有正向联系,尿微量白蛋白水平与DR患者阳虚证、痰湿证程度有正向联系。出血、硬渗、软渗眼底微观改变与阳虚证表现程度呈正向相关。
English Summary:
      To provide reference to standardized clinical syndrome differentiation of type 2 diabetes with retinopathy (DR) through the study on its syndromes and patterns. Methods:Information and data of 104 patients diagnosed as type 2 diabetes with retinopathy in Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine were gathered, input, and analyzed. Results:The highest appearance frequency of the syndromes in 104 patients were phlegm damp syndrome, blood stasis syndrome, yin deficiency syndrome, qi depression syndrome, damp heat syndrome, and qi deficiency syndrome. The frequency of all the above were over 50%, which indicated that among these samples, yin deficiency and qi deficiency were the main patterns for healthy energy and deficiency; phlegm damp, blood stasis, qi depression and damp heat were the main patterns for tip and root. Conclusion: 1) The condition of DR does not have too much to do with the ages of patients, while it is closely relevant to the length of disease course; 2) Diabetic nephropathy, hypertension, and hyperuricemia are relevant to the onset and development of DR; 3) Multiple syndromes and complex of deficiency and excess were the characteristics of DR; 4) The level of glycolated hemoglobin has positive association with phlegm damp syndrome and damp heat syndrome of DR; the level of urinary albumin has positive association with yang deficiency syndrome and phlegm damp syndrome of DR; hemorrhage and microscopic changes of fundi has positive association with yang deficiency syndrome.
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