| 引用本文:夏立营 刘维佳 寇秋爱 周佩云 李跃虹 李明喜 崔坤敏 葛文津.叶黄素治疗年龄相关性黄斑变性的临床研究[J].世界中医药,2013,8(05):. |
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| 叶黄素治疗年龄相关性黄斑变性的临床研究 |
| Clinical Trial of Lutein on Treatment of Age-related Macular Degeneration |
| 投稿时间：2013-01-09 |
| DOI：10.3969/j.issn.1673-7202.2013.05.013 |
| 中文关键词: 临床研究 年龄相关性黄斑变性 叶黄素 |
| English Keywords:Clinical trial Age-related macular degeneration(AMD) Lutein |
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| 中文摘要: |
| 目的:观察叶黄素治疗年龄相关性黄斑变性的临床疗效。方法：采用随机、对照、双盲方法，观察83例患者服食叶黄素咀嚼片前后137只眼睛视力、眼底黄斑变化。结果：治疗组显效11眼，有效31眼，无效32眼，总有效率56.76%；对照组显效0眼，有效19眼，无效44眼，总有效率30.16%。2组比较有统计学意义(P<0.001)。结论：叶黄素对年龄相关性黄斑变性患者眼底表现及视力有一定改善作用。 |
| English Summary: |
| To evaluate the clinical therapeutic effect of Lutein on the treatment of age-related macular degeneration (AMD). Methods:137 eyes of 83 AMD patients were randomized in a controlled, double blind trial. The treatment group was treated with lutein chewable tablets and the control group were treated with placebo. After 3-month treatment, the changes of distant vision and puncta luteum in OCT were observed. Results:The total effective rate of the treatment group was 56.76%, significant better than 30.16% of the control group (P<0.001). Conclusion: Lutein showed therapeutic effect for age-related macular degeneration, such as improving visual activity, elimination of retina edema and atrophying. |
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