| 引用本文:李影华，苏冬梅，白桦.柴胡疏肝散加减治疗肝胃不和型反流性食管炎98例的临床观察[J].世界中医药,2016,(08):. |
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| 柴胡疏肝散加减治疗肝胃不和型反流性食管炎98例的临床观察 |
| Clinical Observation of Modified Bupleurum Liver-Soothing Powder in 98 Reflux Esophagitis Patients with Liver-stomach Disharmony Syndrome |
| 投稿时间：2016-03-22 |
| DOI：10.3969/j.issn.1673-7202.2016.08.011 |
| 中文关键词: 柴胡疏肝散 肝胃不和型 反流性食管炎 |
| English Keywords:Bupleurum Liver-Soothing Powder Liver-stomach disharmony syndrome Reflux esophagitis |
| 基金项目:中国中医科学院所级课题(编号:y2014-04)——“胃食管反流病肝郁脾虚证临床疗效观察” |
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| 中文摘要: |
| 目的:观察柴胡疏肝散加减治疗肝胃不和型反流性食管炎的临床疗效。方法:98例符合入组标准的反流性食管炎患者随机分为治疗组和对照组,治疗组49例予柴胡疏肝散加减200 mL/次,2次/d,口服,对照组49例予雷贝拉唑肠溶胶囊20 mg/次,2次/d,口服,疗程8周,随访4周。结果:治疗组总有效率87.76%、复发率6.38%,对照组总有效率69.39%、复发率23.91%,治疗组无论是总有效率还是复发率均优于对照组（P<0.05)。结论:柴胡疏肝散加减治疗反流性食管炎有较好的临床疗效,且明显优于雷贝拉唑肠溶胶囊,复发率亦降低,值得临床推广。 |
| English Summary: |
| To observe the clinical effect of Reflux esophagitis(RE) treated by Modified Bupleurum Liver-Soothing Powder. Methods: Total 98 patients were divided into two groups, treatment group and control group randomly. The treatment group with 49 patients were treated with oral Modified Bupleurum Liver-Soothing Powder of 200 mL Bid. The control group with 49 patients was treated with oral Rabeprazole enteric-coated capsules of 20 mg Bid. The treatment lasted for 8 weeks, and follow-up for 4 weeks. Results: The total effective rate of the treatment group was 87.76%, and the recurrence rate was 6.38%; the total effective rate of the control group was 69.39%, and the recurrence rate was 23.91%. The curative effect of treatment group was better than the control group(P<0.05) and the recurrence rate was lower(P<0.05). Conclusion: Modified Bupleurum Liver-Soothing Powder treatment of reflux esophagitis has clear effect, and better than Rabeprazole enteric-coated capsules with low recurrence rate, which is worthy of clinical promotion. |
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