世界中医药
文章摘要
引用本文:张雪荣1,陈格格1,陈庆梅1,裴学军2,肖飞2,向希雄3.龙牡壮骨颗粒治疗维生素D缺乏性佝偻病的临床研究[J].世界中医药,2016,(08):.  
龙牡壮骨颗粒治疗维生素D缺乏性佝偻病的临床研究
Clinical Research of Longmu Zhuanggu Granule for Vitamin D Deficiency Rickets
投稿时间:2016-06-30  
DOI:10.3969/j.issn.1673-7202.2016.08.016
中文关键词:  龙牡壮骨颗粒  维生素D缺乏性佝偻病  治疗
English Keywords:Longmu Zhuanggu Granule  Vitamin D deficiency rickets  Treatment
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作者单位
张雪荣1,陈格格1,陈庆梅1,裴学军2,肖飞2,向希雄3 1 湖北中医药大学武汉430065 2 健民集团儿童药物研究院武汉430052 3 湖北省中医院武汉430061 
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中文摘要:
      目的:研究龙牡壮骨颗粒对维生素D缺乏性佝偻病的临床疗效性及安全性。方法:对50例维生素D缺乏性佝偻病患儿给予龙牡壮骨颗粒口服治疗,观察患儿治疗前后疾病及中医证候疗效的改变情况等。结果:疾病疗效、中医证候疗效好转率都达到88%。头部、胸骨骨骼畸形、牙齿迟出前后证候积分差异无统计学意义(P>0.05)。下肢骨骼畸形用药前后证候积分差异有统计学意义(P<0.05)。食欲食量、面色、汗证、肌肉、毛发、精神、夜惊、枕秃用药前后证候积分有统计学意义(P<0.01)。结论:龙牡壮骨颗粒对维生素D缺乏性佝偻病的临床疗效显著,对面色、汗证、肌肉、毛发、精神、夜惊、枕秃症状有明显改善作用,临床上有很好的应用价值及前景。
English Summary:
      To study the treatment of Longmu Zhuanggu Granule for Vitamin D deficiency rickets treatment and its clinical efficacy and safety. Methods: Total 50 cases of Vitamin D deficiency rickets children were given oral treatment of Longmu Zhuanggu Granule, and then their disease and syndrome curative effect before and after treatment were observed. Results: The effective rate and the improving rate of Chinese medicine syndromes reached 88%. The head, chest bone deformity, late teeth scores has no statistical significances before and after the treatment (P>0.05). Lower limb bone malformation syndrome score had significant difference after the treatment (P<0.05). The scores of appetite, amount of foods, complexion, sweat syndrome, muscles, hair, spirit, night terrors, pillow bald had significant differences after the treatment (P<0.01). Conclusion: The clinical curative effect of Longmu Zhuanggu Granule for Vitamin D deficiency rickets is clear, with obvious improvement on some symptoms including the complexion, sweat, muscles, hair, spirit, night terrors, pillow bald, which has a good clinical application value and prospect.
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