| 引用本文:周海娟，陈刚，黄健.益气滋阴中药加灌肠治疗气阴两虚型功能性便秘的短期疗效观察[J].世界中医药,2016,(08):. |
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| 益气滋阴中药加灌肠治疗气阴两虚型功能性便秘的短期疗效观察 |
| Observation of the Short-term Clinical Efficacy of Functional Constipation with Qi and Yin Deficiency Treated with Replenishing Qi and Nourishing Yin Chinese Medicinal and Enema |
| 投稿时间：2015-06-10 |
| DOI：10.3969/j.issn.1673-7202.2016.08.024 |
| 中文关键词: 益气滋阴中药 灌肠 气阴两虚型；功能性便秘 |
| English Keywords:Invigorating qi and nourishing yin Enema Qi and yin deficiency Functional constipation |
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| 中文摘要: |
| 目的:探讨益气滋阴中药加灌肠治疗气阴两虚型功能性便秘的短期临床疗效。方法:将2013年7月到2014年12月因功能性便秘在门诊治疗的患者随机分为中药口服和灌肠的治疗组和单纯中药灌肠的对照组。采用完全自主排便次数（Complete Spontaneous Bowel Movements，CSBMs）、粪便性状评分、排便困难程度评分评估排便改善情况，采用《中医病证诊断疗效标准》中便秘的疗效标准评估临床疗效。结果:1）治疗组组内治疗2周、治疗4周与随访4周平均周CSBMs与治疗前相比，差异有统计学意义（P<0.01）；对照组治疗4周平均周CSBMs与治疗前相比，差异有统计学意义（P<0.05）；治疗组治疗2周、治疗4周与随访4周平均周CSBMs显著高于对照组，相比较差异有统计学意义（P<0.01）。2）治疗组组内治疗2周后、治疗4周后与末次随访粪便性状评分与治疗前相比，差异有统计学意义（P<0.01）；对照组治疗4周后粪便性状评分与治疗前相比，差异有统计学意义（P<0.05）；治疗组治疗2周后、治疗4周后与末次随访粪便性状评分显著高于对照组，相比较差异有统计学意义（P<0.01）。3）治疗组组内治疗2周后、治疗4周后与末次随访排便困难程度评分与治疗前相比，差异有统计学意义（P<0.01）；治疗组治疗2周后、治疗4周后与末次随访排便困难程度评分显著低于对照组，相比较差异有统计学意义（P<0.05或0.01）。4）治疗组治疗4周后有效率89.29%，显著高于对照组60.71%，相比差异有统计学意义（P<0.05）；治疗组末次随访有效率82.14%，显著高于对照组50.00%，相比差异有统计学意义（P<0.05）。结论:益气滋阴中药加灌肠治疗气阴两虚型功能性便秘能改善排便情况，短期临床疗效满意。 |
| English Summary: |
| To investigate the short-term clinical efficacy of functional constipation with qi and yin deficiency treated with replenishing qi and nourishing yin Chinese medicinal and enema. Methods: Patients from July 2013 to December 2014 with functional constipation with outpatient treatment were randomly divided into the therapy group where patients were treated with oral taking Chinese medicinal and enema, and the control group where treated only with Chinese medicinal enema. Improvement of bowel movements was evaluated by CSBMs, stool character score and difficulty degree of defecation score. Clinical efficacy was evaluated according to the constipation curative standard of “the diagnostic standard of tradition Chinese medicine syndromes”. Results:1) In therapy group, the average CSBMs after two weeks′ treatment, four weeks′ treatment and four weeks′ follow-up had significant differences compared with those before treatment (P<0.01); and in control group, average CSBMs of four weeks′ treatment had significant differences compared with that before treatment(P<0.05）; the average CSBMs after two weeks′ treatment, four weeks′ treatment and four weeks′ follow-up of the therapy group were significantly higher than those of the control group (P<0.01). 2) In therapy group, the stool character score after two weeks′ treatment, four weeks′ treatment and four weeks′ follow-up had significant differences compared with that before treatment (P<0.01）; and in control group, stool character score of four weeks′ treatment had significant differences compared with that before treatment(P<0.01）; the stool character score two weeks′ treatment, four weeks′ treatment and four weeks′ follow-up of the therapy group were significantly higher than those of the control group. 3) In therapy group, the difficulty degree of defecation score after two weeks′ treatment, four weeks′ treatment and four weeks′ follow-up had significant differences compared with that before treatment (P<0.01）; and the difficulty degree of defecation score after two weeks′ treatment, four weeks′ treatment and four weeks′ follow-up of the therapy group were significantly lower than those of the control group (P<0.05 or 0.01）.4)In therapy group effective rate of after 4 weeks treatment was 89.29%, significantly higher than 60.71% in the control group, the difference was statistically significant(P<0.05）. In therapy group effective rate of last follow-up was 82.14%, significantly higher than 50.00% in the control group, the difference was statistically significant(P<0.05）. Conclusion: Invigorating qi and nourishing yin Chinese medicinal and enema in the treatment of functional constipation with qi and yin deficiency can improve bowel movements with satisfying short-term clinical efficacy. |
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