世界中医药

作者	单位
孙铭良1，王萍2，仇同革3，刘万亭3	1 山东中医药大学，济南，250000； 2 山东中医药大学第二附属医院心内科，济南，250001； 3 上海医药集团青岛国风药业股份有限公司，青岛，266510

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中文摘要:

目的：观察养心氏片对气虚血瘀型慢性心力衰竭心功能改善的临床效果。方法：选择68例气虚血瘀型慢性心力衰竭患者,随机分为养心氏片组(治疗组)34例和对照组34例,2组均采用常规抗心力衰竭治疗，治疗组在常规治疗基础上,加用养心氏治疗。观察治疗前后临床心功能NYHA分级、左室射血分数、临床症状等变化。结果：治疗4个月后，治疗组左室射血分数治疗前、后比较，治疗后治疗组与对照组组间比较,均有统计学意义(P<0.05)；治疗组对胸闷、憋喘、心悸、水肿、乏力的有效率分别为83%、87%、80%、82%、88%，与治疗前及对照组比较,差异有统计学意义(P<0.05)；治疗组心功能与治疗前及对照组比较,差异有统计学意义(P<0.05)。结论：养心氏片可显著提高慢性心力衰竭患者的心脏功能,提高左室射血分数，显著改善患者临床症状。

English Summary:

To observe the clinical effect of Yangxinshi tablets in the treatment of heart function in chronic heart failure with qi deficiency and blood stasis syndrome. Methods: Total 68 cases of qi deficiency and blood stasis syndrome of chronic heart failure patients were randomly divided into treatment group (34 cases) and control group (34 cases). Two groups received routine treatment but the treatment group also applied Yangxinshi tablets treatment. The clinical cardiac function NYHA grade, left ventricular ejection fraction, clinical symptoms and other factors were evaluated before and after treatment. Results: After 4 months of treatment, the left ventricular ejection fraction had significant differences before and after the treatment in the two groups (P<0.05); the effective rate of chest tightness, hold asthma, heart palpitations, edema, weak efficiency were respectively 83%, 87%, 80%, 82% and 88% in the treatment group; the difference on heart function between the two group and the the difference was significant (P<0.05); cardiac function in the treatment group had significant difference compared with the control group and the results before the treatment (P<0.05). Conclusion: Yangxinshi tablets can effectively improve cardiac function in patients with chronic heart failure, as well as improve left ventricular ejection fraction, which can significantly relieve the clinical symptoms of the patients.

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