| 引用本文:郭玉红1，2，3，戴浩然2，刘清泉1，2，3.脓毒症急性肾损伤相关因素分析[J].世界中医药,2017,(04):. |
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| 脓毒症急性肾损伤相关因素分析 |
| Analysis of relevant factors of sepsis-induced acute kidney injury |
| 投稿时间：2017-03-17 |
| DOI：10.3969/j.issn.1673-7202.2017.04.002 |
| 中文关键词: 脓毒症；急性肾损伤；临床特点 预后 |
| English Keywords:Sepsis Acute kidney injury Clinical features Prognosis |
| 基金项目:北京协和医学基金会“睿E急诊医学研究专项基金”（编号：R2014077） |
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| 中文摘要: |
| 目的:探讨脓毒症并发急性肾损伤（AKI）患者的临床特点及其影响预后的因素。方法:回顾性分析2011年12月至2016年12月入住首都医科大学附属北京中医医院急诊重症监护室的脓毒症患者90例。用单因素及多因素Logistic回归分析研究其临床特点及影响预后的危险因素。结果:90例脓毒症并发AKI患者占42例，AKI组死亡率明显高于非AKI组（P<0.05）。单因素分析显示：肾病史、肺部感染、MODS、CRRT、中药干预和呼吸机的使用是影响AKI恢复的主要因素。多因素分析显示：如果MODS增高和肺部感染存在会增加其死亡风险。结论:器官衰竭数目、及需机械通气支持可作为判断脓毒症并发AKI患者预后的重要依据。 |
| English Summary: |
| To discuss the clinical features of patients with sepsis-induced acute kidney injury(AKI) and the factors that affect prognosis. Methods:A total of 90 sepsis cases in Intensive Care Unit (ICU) of Beijing Hospital of Traditional Chinese Medicine from December， 2011 to December， 2016 were retrospectively analyzed. Simple and multiple logistic regression were used to analyze and study the clinical features and risk factors affecting prognosis. Results:A total of 42 sepsis cases were complicated by AKI. The mortality rate of cases with AKI was evidently higher than the rest without AKI (P<0.05). The analysis by simple logistic regression revealed that the major factors affecting the curing of AKI could be history of nephropathy， pulmonary infection， MODS， CRRT， intervention of Traditional Chinese Medicine and use of respirator. And the analysis by multiple logistic regression revealed that rising of MODS and pulmonary infection might increase the mortality risk. Conclusion:The amount of failure organs， and use of respirator can be taken as important reference for the estimates of the prognosis of patients with sepsis-induced AKI. |
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