| 引用本文:梁立新1，吴彦青2，郭玉红1，2，3，刘清泉1，2，3.脓毒症急性胃肠损伤评估的研究进展[J].世界中医药,2017,(04):. |
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| 脓毒症急性胃肠损伤评估的研究进展 |
| Advances in Evaluation of Acute Gastrointestinal Injury in Sepsis |
| 投稿时间：2017-03-17 |
| DOI：10.3969/j.issn.1673-7202.2017.04.007 |
| 中文关键词: 脓毒症 急性胃肠损伤 急性胃肠损伤分级 胃肠功能障碍评分 瓜氨酸 二胺氧化酶 D-乳酸 肠脂肪酸结合蛋白 |
| English Keywords:Sepsis Acute Gastrointestinal Injury Acute Gastrointestinal Injury Grade Gastrointestinal Failure Score Citrulline Diamine Oxidase D-lactate Intestinal Fatty Acid Binding Protein |
| 基金项目:国家中医药管理局中医临床研究基地业务建设科研专项（编号：JDZX2015303），北京市医院管理局重点医学专业发展计划（编号：ZYLX201611），首都医科大学基础-临床科研合作基金（编号：16JL74） |
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| 中文摘要: |
| 近年来，胃肠道作为脓毒症病理生理过程中最早和最严重受累的器官之一，其重要性逐渐被人们认识。早期、客观、及时、准确的评估脓毒症患者的急性胃肠损伤程度，及早进行干预，可减轻由其诱发的失控性炎性反应，改善脓毒症患者的预后。目前，临床上对脓毒症急性胃肠损伤仍缺乏特异性的诊断指标或体系。为此，作者总结了近几年脓毒症急性胃肠损伤的评分及分级系统、血清生物学标志物的研究进展，为脓毒症急性胃肠损伤的早期诊断及治疗提供一定的参考依据。 |
| English Summary: |
| In recent years， the importance of gastrointestinal tract is gradually recognized， since it is one of the earliest and most seriously affected organs in the course of sepsis. Early and accurate assessment of acute gastrointestinal dysfunction in patients with sepsis can promote timely intervention and thus reduce the uncontrolled inflammatory response caused by the dysfunction. The earlier the treatment starts up， the better prognosis the patients will have. At present， the clinical diagnosis of acute gastrointestinal injury in sepsis is still lack of specific diagnostic indicators or system. Under these circumstances， the author summarized the advances of score and grading system and serum biological markers about acute gastrointestinal injury of sepsis， with the purpose of promoting the early diagnosis and treatment of acute gastrointestinal injury in sepsis. |
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