| 引用本文:孙敏1，邢启凡1，李窦红1，施帆帆1，周玲2，李育红2，耿文忠2，杨国卉2，曹国丽1，崔涛1，王京昆1，朱兆云1.痛舒胶囊治疗过度使用的软组织损伤临床观察(54例)[J].世界中医药,2019,(02):. |
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| 痛舒胶囊治疗过度使用的软组织损伤临床观察(54例) |
| Clinical Observation on Tongshu Capsules in the Treatment of 54 Patients with Soft Tissue Injury Caused by Overuse |
| 投稿时间：2017-06-26 |
| DOI：10.3969/j.issn.1673-7202.2019.02.034 |
| 中文关键词: 痛舒胶囊 软组织损伤 双盲 安慰剂对照 疼痛 有效性 安全性 临床观察 |
| English Keywords:Tongshu Capsules Soft tissue injury Double-blind Placebo-controlled Pain Efficacy Safety Clinical observation |
| 基金项目:云南省科技厅科技领军人才培养计划项目（2014HA001） |
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| 中文摘要: |
| 目的：考察痛舒胶囊治疗由过度使用造成的软组织损伤的安全性和有效性。方法：选取2016年4月至2016年12月楚雄州中医医院门诊收治的由过度使用软组织损伤患者54例，根据是否使用痛舒胶囊分为对照组（n=26）和观察组（n=28），分别在72 h、7 d、14 d及21 d观察患者症状，运用疼痛强度计分（VAS评分）、患者总体印象量表（PGIC）和及总疼痛强度差（SPID）评价其疼痛缓解程度，进而进行有效性和安全性评价。结果：对照组和观察组在用药后72 h、7 d、14 d及21 d VAS、PGIC、SPID的评价差异有统计学意义（P<0.05），且2组受试者给药后72 h、7 d、14 d及21 d d有效率差异有统计学意义（P<0.05）。在用药安全方面，发生了2例不良事件，为胃部不适。结论：痛舒胶囊治疗过度使用造成的软组织损伤安全有效。 |
| English Summary: |
| To evaluate the safety and efficacy of Tongshu Capsules in the treatment of soft tissue injury caused by overuse.Methods:A double-blind，placebo-controlled method was used.According to whether Tongshu Capsule was used or not，the patients were divided into control group (n＝26) and observation group (n＝28).VAS，PGIC and SPID were used to evaluate the degree of pain relief at 72(±2) hours，7(±2) days，14 (±2) days，and 21(±2) days after the medication so as to evaluate the efficacy and safety.Results:The differences of VAS，PGIC and SPID between observation group and control group had statistical significance at 72(±2) hours，7 (±2) days，14 (±2) days，21(±2) days after the medication，and the differences of effective rate also had statistical significance at 7(±2) days，14 (±2) days，21(±2) days after the medication.In the aspect of safety，there appeared 2 cases of adverse reactions of stomach discomfort.Conclusion:It is safe and effective to use Tongshu Capsules in the treatment of soft tissue injury caused by overuse. |
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