| 引用本文:于小林1，张艳霞2，杨效华2，张晓梅2.基于现代文献的特发性肺间质纤维化中医证型及证候要素分布研究[J].世界中医药,2019,(04):. |
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| 基于现代文献的特发性肺间质纤维化中医证型及证候要素分布研究 |
| TCM Syndrome Types and Distribution of Syndrome Factors of Idiopathic Pulmonary Interstitial Fibrosis Based on Modern Documents |
| 投稿时间：2018-01-30 |
| DOI：10.3969/j.issn.1673-7202.2019.04.015 |
| 中文关键词: 特发性肺间质纤维化 证型 证候要素 病位 痰浊 血瘀 气阴两虚 气虚血瘀 痰瘀阻络 |
| English Keywords:Idiopathic pulmonary fibrosis Syndrome types Syndrome factors Location of disease Phlegm turbidity Blood stasis Deficiency of qi and yin Qi deficiency and blood stasis Stagnation of phlegm and blood stasis |
| 基金项目:国家自然科学基金项目(81603577) |
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| 中文摘要: |
| 目的:探讨特发性肺间质纤维化证素分布规律。方法:检索1990—2017年关于特发性肺间质纤维化的文献报道,建立EXCEL2010数据库,导入SPSS 14.0统计软件进行数据频数分布统计。结果:共收集到符合标准的文献69篇。特发性肺间质纤维化常见证型是气阴两虚、气虚血瘀、痰瘀阻络。共提取出证素12个,以气虚、血瘀、痰浊、阴虚多见,累计构成比是83.44%,证候靶点多在肺、经络、肾为主。证素组成形式有4种,以两证素、三证素最为多见。在两证素中,以气虚+阴虚为主,其次是痰+血瘀,作用靶点在肺、肾。结论:本病的主要相关脏腑是肺,涉及到经络、肾等病位,痰、血瘀为主要的病理因素。 |
| English Summary: |
| To investigate the distribution rule of syndrome factors for idiopathic pulmonary fibrosis(IPF). Methods:All the documents of IPF from 1990 to 2017 were retrieved to establish database by EXCEL 2010 and then the data was exported into SPSS 14.0 for frequency distribution static analysis. Results:A total of 69 documents met the criteria were collected. The common syndrome types of IPF were deficiency of both qi and yin，qi deficiency and blood stasis，and stagnation of phlegm and blood. 12 syndrome factors were extracted，and the common factors was deficiency of qi，blood stasis，phlegm turbidity and deficiency of yin. The constituent ratio was 83.44%. The targets were mainly the lung，meridians and collaterals，kidney. There were 4 forms of syndrome factor combination，and forms of 2 or 3 syndrome factors were common. The most common factor among 2-syndrome-factor was deficiency of qi plus deficiency of yin，then phlegm plus blood stasis. The targets were lung and kidney. Conclusion:The major viscera of IPF was the lung，involving meridians and collaterals，kidney，phlegm and blood stasis were the mainly pathological factors. |
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