世界中医药
文章摘要
引用本文:张安晶1,胡元会2,李树斌1,姜北1,孙雪松1,史玮1,魏艺2.益气养阴利水法对冠心病心力衰竭患者BNP、SOD及生命质量影响的研究[J].世界中医药,2019,(04):.  
益气养阴利水法对冠心病心力衰竭患者BNP、SOD及生命质量影响的研究
Effects of Supplementing Qi,Nourishing Yin and Promoting Diuresis on BNP,SOD and Quality of Life in Patients with Coronary Heart Diseases and Heart Failure
投稿时间:2019-03-12  
DOI:10.3969/j.issn.1673-7202.2019.04.028
中文关键词:  益气养阴利水法  心力衰竭  BNP  气阴两虚水停证  生命质量  超氧化物歧化酶  冠心病  明尼苏达量表
English Keywords:Supplementing qi,nourishing yin and promoting diuresis method  Heart failure  BNP  Deficiency of qi and Yin and water stopping syndrome  quality of life  Superoxide dismutase  Coronary heart disease  Minnesota scale
基金项目:中国中医科学院广安门医院南区院级课题项目(Y2015-05)
作者单位
张安晶1,胡元会2,李树斌1,姜北1,孙雪松1,史玮1,魏艺2 1 中国中医科学院广安门医院(南区)心血管科北京102618 2 中国中医科学院广安门医院北京100053 
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中文摘要:
      目的:研究益气养阴利水法对冠心病心力衰竭患者BNP、SOD及生命质量的影响。方法:选取2016年1月至2017年12月广安门医院南区内一科病房收治的气阴两虚水停型心力衰竭患者60例作为研究对象,按照随机数字表法随机分为对照组和观察组,每组30例。对照组给予标准心力衰竭药物治疗,观察组在对照组的基础上给予益气养阴利水中药颗粒剂治疗,观察时间为4周,比较治疗前后2组患者BNP、SOD变化,采用明尼苏达生命质量量表及中医证候积分量表评价患者生命质量变化。结果:2组治疗后BNP均较治疗前下降,同组治疗前后比较,差异均有统计学意义(P<0.05);观察组治疗后BNP较对照组下降明显,2组比较差异有统计学意义(P<0.05)。2组治疗后SOD均较治疗前上升,差异均有统计学意义(P<0.05),观察组治疗后SOD较对照组升高明显,2组比较差异有统计学意义(P<0.05)。2组治疗后明尼苏达生命质量评分均较治疗前下降,差异有统计学意义(P<0.05),观察组治疗后明尼苏达生命质量评分较对照组下降明显,2组比较差异有统计学意义(P<0.05)。观察组治疗后中医证候评分较对照组下降明显,2组比较差异有统计学意义(P<0.05)。结论:益气养阴利水法可有效改善心力衰竭患者的心功能及生命质量。
English Summary:
      To study the effects of supplementing qi,nourishing yin and promoting diuresis method on the BNP,SOD and quality of life of the patients with coronary heart disease and heart failure.Methods:According with standard of the studies in 60 cases of type qi yin deficiency of water stop heart failure patients in Guang'anmen Hospital(South)from January 2016 to December 2017 were randomly divided into the control group(30 cases)and the observation group(30 cases).The control group was admitted the standard heart failure therapy,while the observation group,on the basis of western medicine,was treated with supplementing qi,nourishing yin and promoting diuresis Chinese medicine granules.Observation time was 4 weeks.The BNP changes,the adoption of quality of life scale of Minnesota and TCM syndrome integral scale in patients of the 2 groups were compared before and after the treatment to evaluate patients' quality of life changes.Results:After treatment,the BNP was both decreased and with statistically significant differences(P<0.05).After treatment,the BNP in the observation group was lower than that of the control group(P<0.05).After treatment,SOD was increased than that before treatment and had statistical significance(P<0.05).After treatment in the observation group,SOD was higher than that in the control group and had statistical significance(P<0.05).The quality of life score in the 2 groups after treatment of Minnesota was decreased and with statistically significant differences(P<0.05).Life quality score in the observation group after treatment of Minnesota decreased and statistically significant compared with control group(P<0.05).s After treatment,TCM syndrome score of observation group was lower than that of control group and was statistically significant(P<0.05).Conclusion:The supplementing qi,nourishing yin and promoting diuresis method can improve the cardiac function and quality of life of patients with heart failure.
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