世界中医药
文章摘要
引用本文:赵锐,张丽.养脑宁心颗粒质量标准研究[J].世界中医药,2019,(07):.  
养脑宁心颗粒质量标准研究
Research on Quality Standard of Yangnao Ningxin Granules
投稿时间:2018-05-10  
DOI:10.3969/j.issn.1673-7202.2019.07.007
中文关键词:  养脑宁心颗粒  葛根  葛根素  牡丹皮  山茱萸  枸杞子  薄层色谱法  高效液相色谱法
English Keywords:Yangnao Ningxin Granule  Radix Puerariae  Puerarin  Cortex Moutan Radicis  Fructus Corni  Fructus Lycii  TLC  HPLC
基金项目:陕西省中医药管理局2017~2018年度中医药科学技术课题(ZYMS015)
作者单位
赵锐,张丽 陕西中医药大学第二附属医院咸阳712000 
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中文摘要:
      目的:建立养脑宁心颗粒的质量标准。方法:选取薄层色谱法方法养脑宁心颗粒处方中牡丹皮、山茱萸、枸杞子进行定性鉴别;用高效液相色谱法测定养脑宁心颗粒中葛根指标性成分葛根素的含量。结果:在薄层色谱图中,在与对照药材色谱图相应的位置上,可见相同颜色的牡丹皮、山茱萸、枸杞子荧光斑点相对应;葛根素进样量0.23~1.15 μg,呈良好的线性关系,r=0.999 9,平均回收率:98.5%,RSD为0.81%。结论:该方法简单易行,重复性良好,可作为养脑宁心颗粒制剂质量控制标准。
English Summary:
      To establish the quality standard of Yangnao Ningxin Granules.Methods:TLC method was used to qualitatively identify the Cortex Moutan Radicis,Fructus Corni and Fructus Lycii in the prescription.The content of puerarin in peony was determined by HPLC.Results:In the thin-layer chromatogram,the corresponding spots of the corresponding color of the Cortex Moutan Radicis,Fructus Corni and Fructus Lycii spots correspond to the same color; the puerarin injection volume was 0.23~1.15 μg,showing a good linear relationship(r=0.999 9),average recovery:98.5%,RSD 0.81%.Conclusion:The method is simple,easy to repeat,and can be used as a quality control standard for the preparation.
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