| To explore the clinical effect of invigorating spleen for benefiting lung tuina manipulation in the remission stage of asthma in children,and to provide references for the choice of treatment options for asthma in children.Methods：A total of 80 children with asthma in remission period were enrolled in Dongzhimen Hospital,Beijing University of Chinese Medicine from January 2016 to June 2018.They were numbered according to the order of consultation.The odd number was set as the control group,and the even number was set as the observation group,with 40 cases in each group.After the 2 groups were enrolled,asthma risk factors were assessed and non-drug management strategies,drug control or mitigation programs were formulated.Health education,daily precautions and methods of prevention and control of controllable risk factors were also carried out for the children and their families.On the basis of the above,the patients in the observation group were treated with tuina manipulation of invigorating the spleen and benefiting the lung.The 2 groups were treated for 3 months.The symptoms,pulmonary function and the number of acute episodes were monitored and compared between the 2 groups.The changes of serum levels of human transforming growth factor-1(TGF-β1),forced vital capacity(FVC),forced expiratory volume in 1 s(FEV1）and FEV1/FVC were compared between the 2 groups before and after treatment.The clinical effects of asthma after completion of treatment cycle were compared between the 2 groups.The adverse drug reactions during treatment were compared between the 2 groups.Results：1）After treatment,the total effective rate of the observation group was higher than that of the control group(P<0.05). 2）The scores of clinical symptoms of shortness of breath,spirit,complexion,diet and sweating in the 2 groups were decreased than those before treatment,and the scores of symptoms in the study group were lower than those in the control group(P<0.05). 3）FVC,FEV1 and FEV1/FVC in the 2 groups were significantly increased than those before treatment,and the observation group was higher than the control group(P<0.05). 4）After treatment,the serum level of human TGF-β1 in the 2 groups was significantly increased than that before treatment,and there was no statistically significant difference between the 2 groups(P>0.05). 5）The number of acute episodes in the observation group was smaller than that in the control group(P<0.05). 6）There were no serious adverse drug reactions in the 2 groups during treatment,and there was no significant difference in the general adverse reaction rate between the 2 groups(P>0.05).Conclusion：invigorating spleen for benefiting lung tuina manipulation combined with routine comprehensive treatment can effectively alleviate the clinical symptoms of children with asthma in remission stage,improve the pulmonary function of children,reduce the frequency of acute attacks,and is safe.It has high clinical value for the control and remission of children with asthma in remission stage. |
