| 引用本文:谢德玲1，金洵2，姚利钱1.中西医结合治疗痰湿肥胖型多囊卵巢综合征患者的临床效果[J].世界中医药,2019,(09):. |
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| 中西医结合治疗痰湿肥胖型多囊卵巢综合征患者的临床效果 |
| Combined Treatment of Traditional Chinese and Western Medicine in Polycystic Ovary Syndrome of Phlegm Dampness and Obesity Syndrome |
| 投稿时间：2019-05-22 |
| DOI：10.3969/j.issn.1673-7202.2019.09.017 |
| 中文关键词: 中西医结合治疗 痰湿 肥胖型 多囊卵巢综合征 达英-35 内分泌 代谢 疗效 |
| English Keywords:Combined treatment of Chinese and western medicine Phlegm dampness Obesity Plycystic ovary syndrome Diane-35 Endocrine secretion Metabolism Therapeutic effect |
| 基金项目:国家自然科学基金项目（81603674） |
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| 中文摘要: |
| 目的：探讨中西医结合治疗对痰湿肥胖型多囊卵巢综合征(PCOS)患者内分泌紊乱及代谢的改善作用。方法：选取2017年1月至2018年6月芜湖市第二人民医院收治的辨证为痰湿型的PCOS患者60例作为研究对象，按照随机数字表法分为对照组和观察组，每组30例，比较2组患者经治疗后内分泌指标［卵泡刺激素（FSH）、促黄体生成素（LH）、LH/FSH］，糖脂代谢指标［空腹血糖（FBG）、空腹胰岛素（FINS）、血清胆固醇（TC）、三酰甘油（TG）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇(HDL-C)］和临床疗效。结果：治疗后2组患者临床疗效比较，观察组治疗有效率为83.33%，对照组治疗有效率为60.00%，差异有统计学意义（P<0.05）。治疗后2组患者内分泌指标FSH、LH、LH/FSH）、糖脂代谢指标FBG、FINS、TC、TG、LDL-C，体质量指数、腰臀比较治疗前降低，但HDL-C水平显著上升，差异有统计学意义（P<0.05），治疗后观察组内分泌指标FSH、LH、LH/FSH）、糖脂代谢指标FBG、FINS、TC、TG、LDL-C，体质量指数、腰臀比较治疗前降低，但HDL-C高于对照组，差异有统计学意义（P<0.05）。结论:中西医结合治疗对痰湿肥胖型PCOS患者的内分泌紊乱和代谢有显著改善作用。 |
| English Summary: |
| To investigate the improvement of endocrine disorders and metabolism in patients with phlegm dampness and obesity polycystic ovary syndrome(PCOS)treated by combined Chinese and western medicine.Methods:A total of 60 patients with PCOS of phlegm dampness and obesity syndrome admitted to Second People's Hospital of Wuhu from January 2017 to June 2018 were divided into a control group and an observation group according to random number table,with 30 cases in each group.The endocrine,glycolipid metabolism and clinical efficacy were compared between the 2 groups after treatment.Results:Comparing the clinical efficacy between the 2 groups after treatment,the total effective rate was 83.33% in the observation group,and 60.00% in the control group,and the difference was statistically significant(P<0.05).After treatment,the endocrine index(FSH,LH,LH/FSH),glycolipid metabolism index(FBG,FINS,TC,TG,LDL-C),BMI and waist-to-hip ratio in the 2 groups were lower than before treatment,however,the HDL-C significantly increased with statistically significant difference(P<0.05).These indexes were significantly lower than those in the control group after treatment,and the HDL-C was higher than that in the control group(P<0.05).Conclusion:Combined treatment of Chinese and western medicine can significantly improve the endocrine disorders and metabolism in patients with PCOS of phlegm dampness and obesity syndrome. |
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