世界中医药

作者	单位
李玲1，宋毅2，孙成磊2，商素珍2，李祥2	1 湖北省荆门市第二人民医院药学部，荆门，448000； 2 中药制药共性技术国家重点实验室，临沂，276000

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中文摘要:

目的：观察并分析脉络舒通丸联合盐酸沙格雷酯治疗血栓闭塞性脉管炎(TAO)的临床疗效。方法：选取2016年8月至2018年8月湖北省荆门市第二人民医院收治的血栓闭塞性脉管炎患者102例作为研究对象，按照随机数字表法随机分为对照组和观察组，每组51例。对照组患者给予盐酸沙格雷酯片口服治疗，观察组患者给予盐酸沙格雷酯片联合脉络舒通丸口服治疗。观察并分析2组患者的治疗效果。结果：观察组总有效率为88.24%，对照组总有效率为80.39%，2组比较差异有统计学意义(P<0.05)。结论：脉络舒通丸联合盐酸沙格雷酯可有效缓解血栓闭塞性脉管炎患者的主要临床症状，改善血液流变学指标，治愈率较高，疗效显著。

English Summary:

To observe and analyze the clinical effect of Mailuo Shutong Pills combined with sarpogrelate hydrochloride in the treatment of thromboangiitis obliterans(TAO).Methods:From August,2016 to August,2018,102 patients with thromboangiitis obliterans admitted to Jingmen No.2 People's Hospital who met the inclusion criteria were selected as the study subjects,and were randomly divided into a control group and an observation group according to the random number table method,with 51 patients in each group.Patients in the control group were given oral treatment of sarpogrelate hydrochloride tablets,while those in the observation group were given oral treatment of sarpogrelate hydrochloride tablets combined with Mailuo Shutong Pills.The therapeutic effects of the 2 groups were observed and analyzed.Results:The total effective rate in the observation group was 88.24%,and that in the control group was 80.39% and the difference between the 2 groups was statistically significant(P<0.05).Conclusion:Mailuo Shutong Pill combined with sarpogrelate hydrochloride can effectively alleviate the main clinical symptoms of TAO patients,improve the hemorheology indexes,and have a high cure rate and significant curative effect.

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