| 引用本文:吕予，侯杰军，智冰清，薛瑞文，张敏，张政香.益气养阴活血法与2型糖尿病胰岛β细胞功能相关性研究[J].世界中医药,2019,(09):. |
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| 益气养阴活血法与2型糖尿病胰岛β细胞功能相关性研究 |
| Study on the Relationship Between Boosting Qi，Nourishing Yin and Invigorating Blood Method and Insulin β Cell Function in Type 2 Diabetes Mellitus |
| 投稿时间：2018-08-31 |
| DOI：10.3969/j.issn.1673-7202.2019.09.028 |
| 中文关键词: 益气养阴活血法 胰岛素β细胞 胰岛功能 2型糖尿病 血糖 糖化血红蛋白 血清炎性反应因子 临床疗效 |
| English Keywords:Boosting qi,nourishing yin and invigorating blood method Insulin β cells Pancreatic function Type 2 diabetes Blood glucose Glycosylated hemoglobin Serum inflammatory factors Clinical efficacy |
| 基金项目:陕西省中医药管理局科研项目(LCMS045) |
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| 中文摘要: |
| 目的：观察分析益气养阴活血法与2型糖尿病胰岛素β细胞功能的相关性。方法：回顾性分析2017年1月至2018年1月陕西中医药大学附属医院收治的2型糖尿病患者100例作为研究对象，根据选用治疗方法的不同分为对照组（n=42）和观察组（n=58），对照组按照常规西医治疗，观察组在对照组基础上加益气养阴活血法治疗，观察2组患者经治疗后的胰岛素功能指标水平，血糖，糖化血红蛋白，血清炎性反应因子以及中医证候评分的改善情况，观察2组患者的不良反应发生率。结果：观察组经治疗后的胰岛素功能指标水平，血糖，糖化血红蛋白，血清炎性反应因子以及中医证候评分的改善各个指标的水平改善全部优于对照组，且不良反应发生率较低，差异均有统计学意义（P<0.05）。结论：益气养阴活血法对于2型糖尿病胰岛素β细胞功能具有十分积极的影响作用，能够有效的调节患者的血糖和糖化血红蛋白使其水平降低以及血清炎性反应因子的水平，减轻患者的症状，临床意义重大。 |
| English Summary: |
| To observe and analyze the relationship between boosting qi，nourishing yin and invigorating blood method and insulin β cell function in type 2 diabetes mellitus.Methods:From January 2017 to January 2018，100 patients with type 2 diabetes admitted in the Affiliated Hospital of Shaanxi University of Chinese Medicine were analyzed retrospectively.According to different treatment methods，the patients were divided into observation group(boosting qi，nourishing yin and invigorating blood method and routine western medicine，n＝58）and control group(routine western medicine treatment，n＝42).Levels of insulin function，blood glucose，glycosylated hemoglobin，serum inflammatory factors and improvement of syndrome score in traditional Chinese medicine(TCM）were observed after the treatment in the 2 groups.Incidence of adverse reaction was observed in the 2 groups.Results:In the observation group，the improvement of insulin function index，blood glucose，glycosylated hemoglobin，serum inflammatory factors and TCM syndrome score were better than those in the control group，and the incidence of adverse reaction was lower.There was statistical difference(P<0.05).Conclusion:Boosting qi，nourishing yin and invigorating blood method has a very positive effect on the function of insulin β cells in type 2 diabetes mellitus.It can effectively decreased the levels of patients' blood sugar and glycosylated hemoglobin，and regulate the level of serum inflammatory factors.It can alleviate the symptoms of the patients.The clinical significance is great. |
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