| 引用本文:张玲，林素财，郑永平.温胆汤合越婢汤联合咪唑斯汀治疗脾虚湿蕴型亚急性湿疹的临床观察[J].世界中医药,2019,(09):. |
|
| 温胆汤合越婢汤联合咪唑斯汀治疗脾虚湿蕴型亚急性湿疹的临床观察 |
| Clinical Observation on the Treatment in Subacute Eczema of Spleen Deficiency and Dampness Accumulation by Using Wendan Decoction and Yuebi Decoction Combined with Mizolastine |
| 投稿时间：2018-09-06 |
| DOI：10.3969/j.issn.1673-7202.2019.09.043 |
| 中文关键词: 温胆汤 越婢汤 咪唑斯汀 湿疹 脾虚湿蕴型 EASI评分法 联合用药 不良反应 |
| English Keywords:Wendan Decoction Yuebi Decoction Mizolastine Eczema Spleen deficiency and dampness accumulation type EASI scoring method Drug combination Adverse reactions |
| 基金项目:广东省中医药局科研项目（20171280）；中山市社会公益科技研究专项资金项目（2017B1010） |
|
| 摘要点击次数: 850 |
| 全文下载次数: 935 |
| 中文摘要: |
| 目的：探讨温胆汤合越婢汤联合咪唑斯汀治疗脾虚湿蕴型亚急性湿疹的临床治疗效果。方法：选取2016年6月至2017年6月中山市中医院收治的脾虚湿蕴型亚急性湿疹患者90例作为研究对象，按照随机数字表法随机分为西药组、中药组和联合用药组，每组30例，对3组患者的湿疹面积及严重度指数进行评分，观察比较3组患者的临床治疗效果，对治疗有效的患者随访1个月，观察患者复发情况及用药不良反应。结果：治疗后联合用药组、西药组的红斑、丘疱疹、糜烂及苔藓化症状评分均显著降低（P<0.05），中药组的丘疱疹、糜烂、苔藓化症状改善明显（P<0.05），治疗4周后，3组总有效率差异有统计学意义（P<0.05）、复发率及用药不良反应发生率比较，差异均无统计学意义（P>0.05）。结论：脾虚湿蕴型亚急性湿疹患者采用温胆汤合越婢汤及咪唑斯汀治疗具有较好的治疗效果，建议临床推广应用。 |
| English Summary: |
| To explore clinical efficacy of Wendan Decoction and Yuebi Decoction combined with mizolastine in the treatment of subacute eczema of spleen deficiency and dampness accumulation.Methods:A total of 90 patients with subacute eczema of spleen deficiency and dampness accumulation admitted in the Zhongshan Hospital of Traditional Chinese Medicine(TCM）from June 2016 to June 2017 were selected as research objects，and they were randomly divided into western medicine group，TCM group and combination group according to random number table method，with 30 cases in each group.Eczema area and severity index in the 3 groups were graded.The clinical effects of the three groups were compared.Patients who were effectively treated were followed up for 1 month to observe the recurrence and adverse drug reactions.Results:After the treatment，the symptom scores of erythema，papulovesicle，erosion and lichenification in the combination group and the western medicine group were significantly decreased(P<0.05)，and the symptoms of papulovesicle，erosion and lichenification in the TCM group were significantly improved(P<0.05).After 4 weeks of the treatment，the total effective rates in the 3 groups were statistically different(P<0.05).However，there was no statistical difference in the recurrence rate and the incidence of adverse drug reactions(P>0.05).Conclusion:There is good efficacy in patients with subacute eczema of spleen deficiency and dampness accumulation by using Wendan Decoction and Yuebi Decoction combined with mizolastine，which is worth clinical application. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
