| 引用本文:鲁林源，朱赟，孙琼.手术联合健脾生血片治疗混合痔伴贫血患者的临床观察[J].世界中医药,2019,(10):. |
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| 手术联合健脾生血片治疗混合痔伴贫血患者的临床观察 |
| Clinical Observation on Surgery Combined with Jianpi Shengxue Tablets in the Treatment of Mixed Hemorrhoids with Anemia Patients |
| 投稿时间：2019-09-04 |
| DOI：10.3969/j.issn.1673-7202.2019.10.030 |
| 中文关键词: 混合痔伴贫血 FOCUS超声刀手术 健脾生血片 临床疗效 血红蛋白 血清铁蛋白 不良反应 |
| English Keywords:Mixed hemorrhoids with anemia FOCUS ultrasound knife surgery Jianpi Shengxue Tablets Clinical efficacy Hemoglobin Serum ferritin Adverse reactions |
| 基金项目:中国人口福利基金会妇幼关爱基金——科研支撑计划项目（FY201700820103） |
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| 中文摘要: |
| 目的：研究观察手术联合健脾生血片治疗混合痔伴贫血患者的临床疗效及安全性分析。方法：选取2017年7月至2019年7月上海交通大学第六人民医院收治的混合痔伴贫血患者92例作为研究对象，按照随机数字表法分为对照组和观察组，每组46例。2组患者均行FOCUS超声刀手术。对照组在术后给予生血宝合剂治疗，观察组在术后给予健脾生血片治疗。连续治疗3个月后对2组患者的临床疗效、中医证候积分变化、血液检查各项指标、不良反应发生率等进行统计比较。结果：观察组总有效率为97.83%(45/46)，高于对照组为19.57%(9/46)，差异有统计学意义(P<0.05)。2组患者治疗前，中医证候积分比较，差异无统计学意义（P>0.05），治疗后2组患者中医证候积分均明显下降，观察组积分均明显低于对照组（P<0.05）。治疗前2组患者的红细胞计数(RBC)、血红蛋白(Hb)、红细胞压积(HCT)、红细胞平均体积(MCV)、血清铁蛋白水平(SF)等水平比较，差异无统计学意义(P>0.05)，在治疗第1、2、3个月后，观察组RBC、Hb、HCT、MCV、SF水平均高于对照组，差异有统计学意义(P<0.05)。观察组不良反应发生率为4.35%(2/46)，对照组为8.70%(4/46)，差异无统计学意义(P>0.05)。结论：健脾生血片联合FOCUS超声刀手术治疗混合痔伴贫血患者的临床疗效显著，改善相关中医证候及血常规各项指标，且不良反应发生率低，治疗安全性良好，值得临床推荐应用。 |
| English Summary: |
| To study and observe clinical efficacy of surgery combined with Jianpi Shengxue Tablets in the treatment of mixed hemorrhoids with anemia patients and to analyze its safety.Methods:A total of 92 patients with mixed hemorrhoids and anemia admitted in Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University from July 2017 to July 2019 were selected as subjects.They were divided into observation group and control group according to random number table method，with 46 cases in each group.The 2 groups of patients were treated with FOCUS ultrasound knife surgery.The control group was treated with Shengxuebao Mixture after the surgery，while the observation group was treated with Jianpi Shengxue Tablets after the surgery.After 3 months of continuous treatment，the clinical efficacy，syndrome score changes in traditional Chinese medicine(TCM)，blood test indicators and the incidence of adverse reactions in the 2 groups were statistically compared.Results:The total effective rate in the observation group was 97.83%(45/46)，which was higher than that in the control group 19.57%(9/46)，and the difference was statistically significant(P<0.05).Before the treatment，there was no significant difference in the TCM syndrome scores between the 2 groups(P>0.05).After the treatment，the TCM syndrome scores in the 2 groups were decreased significantly，and the scores in the observation group were significantly lower than those in the control group(P<0.05).There was no significant difference in the levels of RBC，Hb，HCT，MCV and SF between the 2 groups before the treatment(P>0.05).After 1，2 and 3 months of the treatment，the levels of RBC，Hb，HCT，MCV and SF in the observation group were higher than those in the control group，and the difference was statistically significant(P<0.05).The incidence of adverse reactions was 4.35%(2/46)in the observation group and 8.70%(4/46)in the control group，with no significant difference(P>0.05).Conclusion:Jianpi Shengxue Tablets combined with FOCUS ultrasound knife surgery is significantly effective in treating mixed hemorrhoids with anemia patients.It can improve relevant TCM syndrome and blood routine indicators，and the incidence of adverse reactions is low.The treatment is safe and worthy of clinical recommendation. |
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