| 引用本文:张响玲1，马旺生1，陈向忠1，聂柳2，唐莹莹2.儿童支气管哮喘中医辨证舌脉象信息特征及其与肺功能的相关性研究[J].世界中医药,2019,(10):. |
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| 儿童支气管哮喘中医辨证舌脉象信息特征及其与肺功能的相关性研究 |
| Tongue and Pulse Information Characteristics of Syndrome Differentiation in Traditional Chinese Medicine and Its Crrelation with Lung Function in Children with Bronchial Asthma |
| 投稿时间：2018-08-30 |
| DOI：10.3969/j.issn.1673-7202.2019.10.053 |
| 中文关键词: 儿童支气管哮喘 中医要素 舌象信息 脉象信息 肺功能 第一秒钟用力呼气量 肺活量 相关性 |
| English Keywords:Children bronchial asthma TCM elements Tongue information Pulse information lung function Forced expiratory volume in the first second Vital capacity Correlation |
| 基金项目:湖北省卫生计生科研计划项目（2016WH026） |
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| 中文摘要: |
| 目的：探讨儿童支气管哮喘中医辨证舌脉象信息特征及其与肺功能的相关性。方法：选取2017年5月至2018年5月武汉科技大学附属普仁医院收治的儿童支气管哮喘患者112例作为研究对象。根据患儿不同病情发展阶段将其分为发作期组和缓解期组，每组56例，另选择医院同期健康体检患儿50例作为对照组。采用ZBOX-Ⅰ型舌脉象数字化分析仪采集患儿舌象、脉象特征，并同时对患儿肺功能进行检测，分析患儿舌、脉象信息特征及其与肺功能的相关性。结果：112例支气管哮喘患儿舌色以红舌、淡红舌、淡白舌、淡紫舌为主，占96.43%；苔色以白苔、黄苔、浅黄苔为主，占98.21%；舌形舌质以齿痕、胖嫩、裂纹舌为主，占96.43%；苔质以薄苔、厚苔、腻苔为主，占98.21%；脉象以弦脉、滑脉、滑弦脉以及沉滑脉为主，占68.75%；发作期组患儿舌色指数、苔色指数均低于缓解期组及对照组,差异有统计学意义（P<0.05）；发作期组、缓解期组h3、h3/h1明显高于对照组,差异有统计学意义（P<0.05）；发作期组w、w/t均高于缓解期组及对照组,差异有统计学意义（P<0.05）；发作期组者第一秒钟用力呼气量预测值（FEV1.0%）低于缓解期及对照组,差异有统计学意义（P<0.05）；缓解期组FEV1.0%低于对照组,差异有统计学意义（P<0.05）；发作期、缓解期组肺活量预测值（FVC%）均低于对照组,差异有统计学意义（P<0.05）；相关性分析结果：舌色、苔色与FEV1.0%、FVC%正相关（P<0.05），脉象w/t与FEV1.0％、FVC%负相关（P<0.05）。结论：儿童支气管哮喘患者中医辨证舌脉象信息特征是患者病情状况的有效反映，舌色、舌苔参数与肺功能正相关，脉象w/t与肺功能负相关，舌、脉象信息特征可为儿童支气管哮喘的中医临床诊疗提供一定的指导依据。 |
| English Summary: |
| To explore the tongue and pulse information characteristics of syndrome differentiation in traditional Chinese medicine(TCM）in children with bronchial asthma and its correlation with lung function.Methods:A total of 112 children with bronchial asthma admitted in the Puren Hospital Affiliated to Wuhan University of Science and Technology from May 2017 to May 2018 were selected as research subjects.According to different stages of disease development，the children were divided into attack stage group and remission stage group，with 56 cases in each group.Another 50 cases of healthy children in the same period in our hospital were selected as control group.The characteristics of tongue and pulse were collected by ZBOX-I digital tongue and pulse analyzer，and the pulmonary function of the children was detected.The characteristics of tongue and pulse information and their correlation with pulmonary function were analyzed.Results:The tongue color of 112 children with bronchial asthma was mainly red tongue，light red tongue，light white tongue and light purple tongue，accounting for 96.43%; the coating color was mainly white coating，yellow coating and light yellow coating，accounting for 98.21%; the shape and body of tongue was mainly tooth-marked，fat tender and cracked tongue，accounting for 96.43%; the coating texture was mainly thin coating，thick coating and greasy coating，accounting for 98.21%; the pulse manifestation was mainly wiry pulse，slippery pulse，slippery and wiry pulse as well as deep and slippery pulse，accounting for 68.75%.The tongue color index and coating color index of the children in the attack stage group were lower than those in the remission stage group and the control group(P<0.05); the h3 and h3/h1 in the attack stage group and the remission stage group were higher than those in the control group(P<0.05); and the w and w/t in the attack stage group were higher than those in the remission stage group and the control group(P<0.05).The FEV 1.0% in the attack stage group was lower than that in the remission stage group and the control group(P<0.05); the FEV 1.0% in the remission stage group was lower than that in the control group(P<0.05); the FVC% in the attack stage group and the remission stage group was lower than that in the control group(P<0.05); the correlation analysis showed that the tongue color and coating color were positively correlated with the FEV 1.0% and FVC%(P<0.05)，while the pulse w/t was negatively correlated with FEV 1.0% and FVC%(P<0.05).Conclusion:The information characteristics of tongue and pulse in children with bronchial asthma are effective reflections of patients' condition.The parameters of tongue color and tongue coating are positively correlated with lung function，while the w/t of pulse is negatively correlated with lung function.The information characteristics of tongue and pulse can provide certain guidance for TCM clinical diagnosis and treatment in children with bronchial asthma. |
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