| 引用本文:何洪俊，李，进，黄新强.中药免煎颗粒及中药饮片所含有效成分的对比研究[J].世界中医药,2019,(11):. |
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| 中药免煎颗粒及中药饮片所含有效成分的对比研究 |
| A Comparative Study on the Effective Components of Chinese Herbal Medicine in Decocting-Free Granules and Decocting Pieces |
| 投稿时间：2018-10-25 |
| DOI：10.3969/j.issn.1673-7202.2019.11.012 |
| 中文关键词: 中药免煎颗粒 中药饮片 有效成分 黄芪甲苷 高效液相色谱法 大黄酚 大黄酸 大黄素 |
| English Keywords:Decocting-free granules of Chinese herbal medicine Decocting pieces of Chinese herbal medicine Active ingredients Astragaloside High performance liquid chromatography Chrysophanol Chrysophanic acid Emodin |
| 基金项目:滁州市科技指导性计划项目(201501) |
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| 中文摘要: |
| 目的：研究对比中药免煎颗粒及中药饮片所含有效成分。方法：选取深圳三九现代中药有限公司生产的大黄中药免煎颗粒与大黄中药饮片，以高效液相色谱法检测大黄中药免煎颗粒与大黄中药饮片中大黄酚、大黄酸、大黄素的含量。同时，采用高效液相色谱法检测大黄中药免煎颗粒与大黄中药饮片中黄芪甲苷的含量。结果：大黄免煎颗粒中大黄酚、大黄酸、大黄素含量分别为3.50 mg/g、9.44 mg/g、3.13 mg/g，大黄饮片中大黄酚、大黄酸、大黄素含量分别为3.34 mg/g、9.57 mg/g、3.05 mg/g。黄芪饮片中的黄芪甲苷含量分别为0.80 mg/g、0.83 mg/g。结论：大黄中药免煎颗粒与大黄中药饮片中大黄酚、大黄酸、大黄素以及黄芪甲苷的含量差异不明显，在临床实际工作中可根据患者的具体情况灵活选用。 |
| English Summary: |
| To study and compare the active ingredients contained in decocting-free granules and decocting pieces of Chinese herbal medicine.Methods:The content of chrysophanol，chrysophanic acid and emodin in Radix et Rhizoma Rhei decocting-free granules and Radix et Rhizoma Rhei decocting pieces produced by Shenzhen Sanjiu Modern Chinese medicine Co.，Ltd.was detected by high performance liquid chromatography(HPLC).Meanwhile，HPLC method was also used to determine the content of astragaloside in Radix et Rhizoma Rhei decocting-free granules and Radix et Rhizoma Rhei decocting pieces.Results:The contents of chrysophanol，chrysophanic acid and emodin in Radix et Rhizoma Rhei decocting-free granules were 3.50 mg/g，9.44 mg/g，3.13 mg/g，respectively.The contents of chrysophanol，chrysophanic acid and emodin in Radix et Rhizoma Rhei decocting pieces were 3.34 mg/g，9.57 mg/g and 3.05 mg/g，respectively.The contents of astragaloside in Radix Astragali seu Hedysari decocting pieces were 0.80 mg/g and 0.83 mg/g respectively.Conclusion:There is no significant difference in the content of chrysophanol，chrysophanic acid，emodin and astragaloside in Radix et Rhizoma Rhei decocting-free granules and Radix et Rhizoma Rhei decocting pieces.It can be selected flexibly according to the specific conditions of patients in clinical practice. |
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