| 引用本文:汤舒，陈永刚，邹吉利.中药材黄芪中无机元素含量的环境影响因素的Logistic回归分析[J].世界中医药,2019,(12):. |
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| 中药材黄芪中无机元素含量的环境影响因素的Logistic回归分析 |
| Logistic Regression Analysis of Environmental Factors Influencing the Content of Inorganic Elements in Radix Astragali seu Hedysari |
| 投稿时间：2018-12-18 |
| DOI：10.3969/j.issn.1673-7202.2019.12.013 |
| 中文关键词: 黄芪 无机元素 生态环境 中药材 Logistic回归分析 影响因素 生态因子 回归方程 |
| English Keywords:Radix Astragali seu Hedysari Inorganic elements Ecological environment Chinese herbal medicine Logistic regression analysis Influencing factors Ecological factors Regression equation |
| 基金项目:武汉市卫生计生科研基金资助项目（WZ15B10) |
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| 中文摘要: |
| 目的：研究中药材黄芪中无机元素含量的环境影响因素并予以Logistic回归分析。方法：选取2016年3月至2018年3月武汉市第三医院购买的源自不同采集地的中药材黄芪20批进行研究，采用微波消解以及全发射X射线荧光光谱法分别测定20批黄芪中无机元素（包括K、Ca、Cr、Mn、Fe、Ni、Cu、Zn、As、Cd、Ba、Pb）的含量。并通过逐步Logistic回归分析中药材黄芪中无机元素含量与海拔、经度、维度、坡向以及坡度5个生态因子的关系。结果：20批黄芪药材中K、Ca、Cr、Mn、Fe、Ni、Cu、Zn、As、Cd、Ba、Pb存在一定差异。将20批黄芪采集点的生态因子作为自变量，将样品中的无机元素含量作为因变量，去除无显著影响的自变量，建立多元线性回归方程。并将海拔、经度、维度、坡向以及坡度5个生态因子分别记为X1、X2、X3、X4、X5，将12种无机元素的含量分别记为Y1（K）、Y2（Ca）、Y3（Cr）、Y4（Mn）、Y5（Fe）、Y6（Ni）、Y7（Cu）、Y8（Zn）、Y9（As）、Y10（Cd）、Y11（Ba）、Y12（Pb）。其中Y4、Y6、Y9、Y10、Y12未选上任何自变量，剩余7种无机元素含量可能与环境因素存在密切相关，其回归方程如下：Y1=-1.829×105+6.031X1+4.516×103X2（R=0.725）；Y2=-1.533×105+3.930×103X2（R=0.895）；Y3=2.386+5.260X4（R=0.747）；Y5=-13.800+6.812×103X5（R=0.438）；Y7=1.877+1.409X4+70.006X5（R=0.688）；Y8=1.288+2.801×102X5（R=0.639）；Y11=42.477-0.036X1+3.412×102X5（R=0.654）。结论：中药材黄芪中无机元素含量受环境影响较为明显，且与海拔、经度、维度、坡向以及坡度存在密切相关，值得临床重点关注。 |
| English Summary: |
| To study the environmental factors influencing the content of inorganic elements in Radix Astragali seu Hedysari and to conduct logistic regression analysis.Methods:A total of 20 batches of Chinese herbal medicine Radix Astragali seu Hedysari from different collection sites purchased from Wuhan Third Hospital from March 2016 to March 2018 were selected for microwave digestion and full emission X-ray fluorescence spectrometry to determine the inorganic elements in 20 batches of Radix Astragali seu Hedysari.(including the contents of K，Ca，Cr，Mn，Fe，Ni，Cu，Zn，As，Cd，Ba，Pb).Through the stepwise logistic regression analysis，the relationship between the content of inorganic elements in Chinese medicinal materials Radix Astragali seu Hedysari and the 5 ecological factors of altitude，longitude，dimension，aspect and slope was analyzed.Results:There were some differences in K，Ca，Cr，Mn，Fe，Ni，Cu，Zn，As，Cd，Ba and Pb in 20 batches of Radix Astragali seu Hedysari.The ecological factors of 20 batches of Radix Astragali seu Hedysari collection points were used as independent variables，and the inorganic element content in the sample was used as the dependent variable to remove the independent variables with no significant influence，and a multiple linear regression equation was established.The 5 ecological factors of altitude，longitude，dimension，aspect and slope are recorded as X1，X2，X3，X4 and X5，respectively.The contents of 12 inorganic elements were recorded as Y1(K)，Y2(Ca)and Y3 respectively.(Cr)，Y4(Mn)，Y5(Fe)，Y6(Ni)，Y7(Cu)，Y8(Zn)，Y9(As)，Y10(Cd)，Y11(Ba)，Y12(Pb).Among them，Y4，Y6，Y9，Y10，Y12 had not selected any independent variables，and the remaining 7 inorganic elements may be closely related to environmental factors.The regression equation was as follows：Y1=-1.829×105+6.031X1+4.516×103X2(R=0.725); Y2=-1.533×105+3.930×103X2(R=0.895); Y3=2.386+5.260X4(R=0.747); Y5=-13.800+6.812×103X5(R=0.438); Y7=1.877+1.409X4+70.006X5(R=0.688); Y8=1.288+2.801×102X5(R=0.639); Y11=42.477-0.036X1+3.412×102X5(R=0.654).Conclusion:The content of inorganic elements in Radix Astragali seu Hedysari is significantly affected by the environment，and is closely related to altitude，longitude，dimension，slope direction and slope，which is worthy of clinical attention. |
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