世界中医药
文章摘要
引用本文:褚扬1,周王谊1,吴江1,乔淼1,王婉琦1,马晓慧1,周水平1,郝海平2.新型冠状病毒肺炎治疗中应关注肝损伤及防治中药概述[J].世界中医药,2020,(02):.  
新型冠状病毒肺炎治疗中应关注肝损伤及防治中药概述
The Treatment of Corona Virus Disease 19 (COVID-19) Should Focus on Liver Injury and the Overview of Prevention and Treatment of Traditional Chinese Medicines(TCMs)
投稿时间:2020-02-14  
DOI:10.3969/j.issn.1673-7202.2020.02.002
中文关键词:  新型冠状病毒  肺炎  肝损伤  病理机制  炎性反应  中草药  中成药  中药药理
English Keywords:2019-nCoV  Pneumonia  Liver injury  Pathological mechanism  Inflammation  Chinese herbal medicines  Chinese patent medicines  Pharmacology of Traditional Chinese medicines
基金项目:天津市科技支撑重点项目(JK1802)
作者单位
褚扬1,周王谊1,吴江1,乔淼1,王婉琦1,马晓慧1,周水平1,郝海平2 1 创新中药关键技术国家重点实验室,天士力医药集团股份有限公司,天津300410
2 中国药科大学,南京,210009 
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中文摘要:
      较大比例的新型冠状病毒感染者在接受抗病毒治疗过程中出现了肝功能异常现象,进而导致脓毒症或感染性休克的发生,需引起临床工作者的关注。多年来,中医药在临床用于肝损伤保护方面发挥了重要作用,其功效得到了普遍的肯定。本文将从新型冠状病毒所致肝损伤的机制、病毒和药物所致肝损伤的病理变化以及常用防治肝损伤的中药及其制剂进行综述,以期为新型冠状病毒肺炎(NCP)患者的肝损伤防治提供参考支持。
English Summary:
      A large proportion of patients with severe acute respiratory syndrome coronavirus 2 infection showed abnormal liver function during the antiviral treatment,which led to sepsis or septic shock,thus causing widespread concern among clinicians. Over the years,traditional Chinese medicines (TCMs) have played an important role in the clinical application of liver injury protection,and its efficacy has been widely recognized. The paper reviewed the mechanism of liver injury caused by 2019-nCoV,the pathological changes of liver injury caused by viruses and drugs,and the TCMs and preparations commonly used to prevent and cure liver injury,in order to provide reference support for the prevention and treatment of liver injury in patients with Novel Coronavirus Pneumonia (NCP).
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