| 引用本文:刘洋1，梁腾霄2.肝性脑病与血管性痴呆的文献证素比较研究[J].世界中医药,2020,(02):. |
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| 肝性脑病与血管性痴呆的文献证素比较研究 |
| A Comparative Study on Syndrome Elements Between Literatures on Hepatic Encephalopathy and Vascular Dementia |
| 投稿时间：2018-11-21 |
| DOI：10.3969/j.issn.1673-7202.2020.02.022 |
| 中文关键词: 肝性脑病 血管性痴呆 辨证论治 证候 证素 病机 比较 文献研究 |
| English Keywords:Hepatic encephalopathy(HE) Vascular dementia(VD) Syndrome differentiation Syndromes Syndrome elements Pathogenesis Comparison Literature research |
| 基金项目:国家中医临床研究基地业务建设科研专项课题(JDZX2015301) |
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| 中文摘要: |
| 目的:总结肝性脑病中医证素特点,并与血管性痴呆比较,突出该病病机特点,为今后研究肝性脑病和轻微型肝性脑病提供借鉴。方法:按照检索策略检出符合纳入标准和排除标准的文献,提取证候和证素信息,总结肝性脑病中医证素特点,并与血管性痴呆研究结果进行比较。结果:1)肝性脑病以热毒内陷心包、痰蒙清窍、痰热腑实,腑气不通、阴阳俱脱、湿热蒙窍、瘀阻清窍、肝风内动、气阴两竭、痰火扰心、肝脾失调等证型多见,其中实证较多。2)肝性脑病组火热、湿、毒等实邪扰动心神,风邪内动所致比例明显高于血管性痴呆组,而阴虚、血瘀、气虚比例明显低于血管性痴呆组,湿、风、疫毒为肝性脑病组特有。结论:肝性脑病病位以心、肝为主,病性以实邪为多,兼有虚实夹杂。实以火热、痰、毒扰动清窍为主,虚以阴虚、气虚为主。 |
| English Summary: |
| To summarize characteristics of syndrome elements in traditional Chinese medicine(TCM)on hepatic encephalopathy(HE).To compare it with vascular dementia(VD)in order to highlight pathogenic characteristics of the disease and provide reference for future study on HE and minimal hepatic encephalopathy(MHE).Methods:In accordance with retrieval strategy, literatures that met inclusion criteria and exclusion criteria were screened out.Information of syndromes and syndrome elements was extracted, the characteristics of TCM syndrome elements of HE were summarized, and they were compared with the study results of VD.Results:1)HE was characterized by syndromes of heat-toxin invading pericardium, orifices confused by phlegm, excessive fu-organ caused by phlegm-heat, obstruction of fu-organ qi, yin-yang collapse, orifices confused by damp-heat, orifices obstructed by stasis, internal stirring of liver wind, exhaustion of both qi and yin, phlegm-fire disturbing heart, and disorder of liver and spleen, most of which were excess syndromes. 2)In HE group, proportions of fire-heat, dampness, toxin and other excessive pathogens disturbing heart and mind, as well as internal stirring of wind pathogens were significantly higher than those in VD group, while proportions of yin deficiency, blood stasis and qi deficiency were significantly lower than those in the VD group.Dampness, wind and pestilent toxin were special for the HE group.Conclusion:The location of HE is mainly heart and liver.The disease is mainly characterized by excessive pathogens, also intermingled deficiency and excess.Excessive pathogens mainly include fire-heat, phlegm and toxin disturbing orifices, while deficient pathogens are mainly yin deficiency and qi deficiency. |
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