| 引用本文:赵有利1，范小涛2.以痰瘀毒论治动脉硬化闭塞症的理论初探[J].世界中医药,2020,(02):. |
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| 以痰瘀毒论治动脉硬化闭塞症的理论初探 |
| Theory Exploration on Treating Arteriosclerosis Occlusion Based on Phlegm, Blood Stasis and Toxin |
| 投稿时间：2019-06-12 |
| DOI：10.3969/j.issn.1673-7202.2020.02.028 |
| 中文关键词: 痰瘀毒 动脉硬化闭塞症 理论 |
| English Keywords:Phlegm, blood stasis and toxin Arteriosclerosis occlusion Theory |
| 基金项目:南京市卫计委第15批科技发展项目(201715055) |
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| 中文摘要: |
| 综合中医药文献多数学者认为痰瘀毒三邪致病使动脉硬化闭塞症(ASO)在治疗上颇为棘手。本文初步对痰瘀毒在ASO中病因病机的理论基础进行归纳,并结合临床典型验案探讨运用解毒化痰、祛瘀通脉法治疗血脉瘀阻、热毒内蕴型ASO发病的作用机制。为进一步研究解毒化痰祛瘀煎剂干预ASO脂质代谢、血液流变、多种炎性反应因子等因素在发挥何种作用,从而为深化中医痰瘀毒理论打下基础。为缩短ASO治愈时间,提高疗效,减少截肢率,寻求中西医结合治疗该病的佳径。 |
| English Summary: |
| Most scholars in literatures of traditional Chinese medicine(TCM)think that the pathogenesis of phlegm, blood stasis and toxin makes the treatment of arteriosclerosis occlusion(ASO)rather difficult.This paper summarizes the theoretical basis of etiology and pathogenesis of phlegm, blood stasis and toxin in ASO, and explores the mechanism of detoxifying and phlegm-resolving as well as blood stasis-removing and vessel-dredging methods in the treatment of ASO with blood stasis in vessels and internal amassment of heat-toxin, referring to typical clinical cases.To further study the role of Jiedu Huatan Quyu Decoction in the intervention of ASO lipid metabolism, hemorrheology, a variety of inflammatory factors and other factors, so as to lay a foundation for deepening the theory of phlegm, blood stasis and toxin in TCM.To shorten treatment time of curing ASO, enhance efficacy and reduce amputation rate, and thus to look for a better way to treat the disease by integrated traditional Chinese and western medicine. |
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