| 引用本文:安洁琼，李昊，孙明明.针刺辅助治疗急性脑出血的疗效及安全性分析[J].世界中医药,2020,(06):. |
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| 针刺辅助治疗急性脑出血的疗效及安全性分析 |
| Clinical Analysis of Acupuncture Combined with Nimodipine in the Treatment of Acute Cerebral Hemorrhage |
| 投稿时间：2019-02-20 |
| DOI：10.3969/j.issn.1673-7202.2020.06.016 |
| 中文关键词: 急性脑出出血 针刺 尼莫地平 神经功能缺损 脑血流动力学 神经损伤 炎性反应 不良反应 |
| English Keywords:Acute cerebral hemorrhage Acupuncture Nimodipine Neurologic impairment Cerebral hemodynamics Nerve injury Inflammatory response Adverse reactions |
| 基金项目:2015年度河南省医学科技攻关计划项目(201504048) |
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| 中文摘要: |
| 目的:探讨针刺辅助治疗急性脑出出血的疗效,分析治疗安全性。方法:回顾性分析2015年6月至2017年12月河南省周口市中心医院收治的急性脑出血患者80例作为研究对象。按照治疗方案不同分为对照组(n＝43)和观察组(n＝37)，对照组患者接受常规＋尼莫地平治疗，观察组患者接受常规＋尼莫地平＋针刺治疗)。比较2组治疗后美国国立卫生研究院脑卒中量表(NIHSS)评分值、脑血流动力学指标、血清中脑损伤指标、炎性反应相关指标水平,治疗不良反应的差异。结果:治疗后,观察组的NIHSS评分值低于对照组;Vm、PI的水平高于对照组,RI的水平低于对照组;GFAP的含量高于对照组,MBP、NSE的含量低于对照组;TGF-β1、ICAM-1、IL-8、TNF-α的含量低于对照组(P<0.05)。2组治疗不良反应发生率的差异无统计学意义(P>0.05)。结论:针刺辅助治疗在优化急性脑出血患者病情方面具有积极作用,同时具有良好的治疗安全性。 |
| English Summary: |
| To explore the efficacy of acupuncture in the assisted treatment of acute cerebral hemorrhage and analyze the safety.Methods:A retrospective analysis of 80 patients with acute cerebral hemorrhage admitted to Zhoukou Central Hospital, Henan Province from June 2015 to December 2017 was taken as the research object.According to different treatment schemes, they were divided into a control group (n＝43) and an observation group (n＝37).Patients in the control group received conventional+nimodipine treatment, and patients in the observation group received conventional+nimodipine+acupuncture treatment.The difference between the two groups of NIHSS scores, cerebral hemodynamics indexes, serum brain damage indexes, inflammatory response-related indexes, and treatment-related adverse reactions were compared after treatment.Results:After treatment, the NIHSS score of the observation group was lower than that of the control group; the levels of Vm and PI were higher than the control group, and the levels of RI were lower than the control group; the content of GFAP was higher than that of the control group, and the content of MBP and NSE were lower than that of the control group; The contents of TGF-β1, ICAM-1, IL-8 and TNF-α were lower than those of the control group (P <0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion:Acupuncture assisted therapy has a positive role in optimizing the condition of patients with acute cerebral hemorrhage, and has good treatment safety. |
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