| 引用本文:谢勤，华东平.益气化痰消瘿方对桥本甲状腺炎患者甲状腺功能的影响[J].世界中医药,2020,(18):. |
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| 益气化痰消瘿方对桥本甲状腺炎患者甲状腺功能的影响 |
| Effects of Yiqi Huatan Xiaoying Formula on Thyroid Function in Patients with Hashimoto's Thyroiditis |
| 投稿时间：2020-03-27 |
| DOI：10.3969/j.issn.1673-7202.2020.18.022 |
| 中文关键词: 桥本甲状腺炎 益气化痰消瘿方 甲状腺功能 甲状腺自身抗体 |
| English Keywords:Hashimoto's thyroiditis Yiqi Huatan Xiaoying Formula Thyroid function Thyroid autoantibodies |
| 基金项目:安徽省卫计委中医药科研课题(2016zy101) |
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| 中文摘要: |
| 目的:益气化痰消瘿方联合优甲乐对桥本甲状腺炎(HT)患者甲状腺功能的影响。方法:选取2017年7月至2019年12月铜陵市中医医院收治的HT患者69例作为研究对象,按照随机数字表法随机分为对照组(n=35)与观察组(n=34),对照组采用优甲乐和硒酵母片治疗,观察组在对照组的基础上加用益气化痰消瘿方治疗,2组患者均连续治疗12周。比较2组患者临床疗效及中医症候积分变化,检测并比较2组患者甲状腺激素、自身抗体水平。结果:治疗后,观察组总有效率为85.29%,高于对照组的62.86%(P<0.05);与治疗前比较,治疗后2组患者甲状腺肿、颜面肢体水肿、神疲乏力、畏寒肢冷等中医证候积分均下降,且观察组低于对照组(P<0.01);与治疗前比较,治疗后2组患者血清TSH、TPOAb、TGAb水平降低,且观察组低于对照组(P<0.01);2组患者FT3、FT4水平升高(P<0.01),且观察组高于对照组(P<0.01)。结论:益气化痰消瘿方联合优甲乐治疗HT可降低患者甲状腺激素水平、自身抗体水平,从而改善患者甲状腺功能,促进患者临床症状缓解。 |
| English Summary: |
| To explore the effects of Yiqi Huatan Xiaoying Formula combined with euthyrox on thyroid function in patients with hashimoto's thyroiditis(HT).Methods:A total of 69 cases of patients with HT in Tongling Hospital of Traditional Chinese Medicine from July，2017 to Dec.2019 were selected as the study objects and divided randomly into a control group(n=35)and an observation group(n=34).The control group were treated with euthyrox and selenious yeast tablets，and study group were treated with Yiqi Huatan Xiaoying Formula on the basis of control group.The 2 groups were treated for 12 weeks continuously.The clinical efficacy of 2 groups and the TCM syndrome score were compared，and the levels of thyroid hormones，autoantibodies were measured and compared.Results:The total effective rate of the treatment group was 85.29% after treatment，which was higher than 62.86% of control group(P<0.05); Compared with those before treatment，the TCM syndrome scores such as goiter，facial limb edema，mental fatigue，fear of cold and cold limb of 2 groups decreased evidently after treatment，and the observation group was lower than control group(P<0.01).Compared with those before treatment，the levels of TSH，TPOAb，TGAb in the 2 groups were significantly lower，and the observation group was lower than the control group(P<0.05 or P<0.01).The FT3、FT4 level of the 2 groups increased(P<0.01)，and the study group was higher than the control group(P<0.01).Conclusion:Yiqi Huatan Xiaoying combined with euthyrox in treating HT can reduce the levels of thyroid hormone，autoantibodies factors in patients，thereby improving patients 'thyroid function and promoting patients' clinical symptoms. |
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