世界中医药

作者	单位
陈红映1，2，孙建辉2，于泽玥2，李洪梅1，2，陈敏3	1 云南中医药大学，昆明，650500； 2 中国中医科学院中药研究所，北京，100700； 3 中国中医科学院中药资源中心，北京，100700

摘要点击次数: 307

全文下载次数: 0

中文摘要:

目的：探讨玛咖-人参水煎液对小鼠免疫功能的影响。方法：通过碳廓清试验、小鼠腹腔巨噬细胞吞噬鸡红细胞试验、绵羊红细胞诱导的小鼠迟发型变态反应试验、ConA诱导的小鼠淋巴细胞转化试验（MTT法）、Jerne改良玻片法测定抗体生成细胞数试验、小鼠血清溶血素的测定，研究玛咖-人参水煎液对小鼠免疫功能的影响。结果：与空白组比较，玛咖-人参水煎液低、中、高剂量组均可明显提高小鼠吞噬指数（P<0.05或P<0.01），玛咖-人参水煎液低、中、高剂量组均可明显提高小鼠巨噬细胞吞噬鸡红细胞吞噬率（P<0.05或P<0.01）和吞噬指数（P<0.01），玛咖-人参水煎液中、高剂量组可明显提高小鼠足趾肿胀度（P<0.05），玛咖-人参水煎液高剂量组可明显提高小鼠溶血空斑数（P<0.01）。结论：玛咖-人参水煎液能提高小鼠单核-巨噬细胞功能、细胞免疫功能和体液免疫功能。

English Summary:

To investigate the effects of Maka Renshend Decoction on immune function of mice.Methods:Antibody production was measured by carbon clearance test,mouse peritoneal macrophage phagocytic chicken red blood cell test,sheep red blood cell-induced delayed-type allergy test in mice,ConA-induced mouse lymphocyte transformation test (MTT method),and Jerne modified slide method Cell number test,determination of mouse serum hemolysin,and the effect of Maka Renshen Decoction on the immune function.Results:Compared with the blank control group, the low, middle and high dose Maka Renshen Decoction groups could significantly increase the phagocytic index of mice (P<0.05 or P<0.01). The low, medium and high dose groups of Maka Renshen Decoction can significantly increase the phagocytosis rate of mouse macrophages and chicken red blood cells (P<0.05 or P<0.01) and phagocytic index (P<0.01). The medium and high-dose groups of Maka Renshen Decoction can significantly increase the swelling of the toes of mice (P<0.05), and the high-dose group of Maka Renshen Decoction can obviously increase the number of hemolytic plaques in mice (P<0.01).Conclusion:Maka Renshen Decoction can improve the function of monocyte-macrophage,cellular immunity and humoral immunity in mice.

查看全文查看/发表评论下载PDF阅读器