| 引用本文:彭菊琴1，张艺楠2，彭娴3，陈芳玲2，李春岩4.射血分数保留心力衰竭气虚证与并发症及超声心动图的相关性[J].世界中医药,2021,(07):. |
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| 射血分数保留心力衰竭气虚证与并发症及超声心动图的相关性 |
| Relationship between Qi Deficiency Syndrome of Heart Failure with Preserved Ejection Fraction with Comorbidities and Echocardiography Indicators |
| 投稿时间：2020-02-09 |
| DOI：10.3969/j.issn.1673-7202.2021.07.021 |
| 中文关键词: 射血分数保留心力衰竭 气虚证 并发症 超声心动图 舒张功能 相关性 |
| English Keywords:Heart failure with preserved ejection fraction(HFpEF) Qi-deficiency syndrome Comorbidity Echocardiography Diastolic function Relativity |
| 基金项目:国家重点研发计划项目（2017YFC1700100）；北京市科技计划项目（Z171100001717024） |
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| 中文摘要: |
| 目的：探讨射血分数保留心力衰竭（HFpEF）气虚证与并发症、超声心动图指标的相关性。方法：采用横断面研究方法，选取2017年12月至2018年12月中日友好医院收治的HFpEF气虚证患者165例作为研究对象，按照中医四诊、并发症信息，并计算气虚证积分，根据气虚证积分分为气虚重证组（n=98）和气虚轻证组（n=67），同时纳入非心力衰竭非气虚证患者60例作为对照组。所有患者均完善多普勒超声心动图检查。结果：气虚证与并发症Logistic回归分析发现，贫血（OR＝0.214,95%CI为0.111～0.447,P=0.000）、糖尿病（OR＝0.054,95%CI为0.006～0.113,P=0.036）、慢性肾脏病（OR＝0.057,95%CI为0.001～0.114,P=0.046）,是气虚证形成的危险因素。气虚证与超声心动图指标的相关性研究发现，气虚重证组较气虚轻证组、对照组二尖瓣环侧壁舒张早期最大速度（e'）更低（4.37 vs. 4.88 vs. 5.54，P=0.041，P=0.000），二尖瓣口舒张早期峰值血流速度（E）/e'更高（22.74 vs. 18.09 vs. 11.96，P=0.012，P=0.000）。结论：HFpEF气虚证形成与并发症分布以及心脏舒张功能受损有关。 |
| English Summary: |
| To explore the relationship between qi-deficiency syndrome of heart failure with preserved ejection fraction(HFpEF)with comorbidities and echocardiography.Methods:Using a cross-sectional study method，the information about four diagnostic methods of TCM and comorbidities in 165 HFpEF patients with qi-deficiency syndrome admitted by China-Japan Friendship Hospital from December 2017 to December 2018 were collected.According to the results of calculating scores of qi-deficiency syndrome，the patients were divided into qi-deficiency severe syndrome group(98 cases)and qi deficiency slight syndrome group(67 cases).And 60 patients without heart failure and qi-deficiency syndrome were enrolled as the control group.The measurement of Doppler echocardiography was finished in all patients.Results:The result of logistic regression analysis of qi-deficiency syndrome and comorbidities was that anemia ［OR＝0.214，95%CI(0.111 to 0.447)，P=0.000］，diabetes ［OR＝0.054，95%CI(0.006 to 0.113)，P=0.036］，chronic kidney disease ［OR＝0.057，95%CI(0.001 to 0.114)，P=0.046］ were risk factors for the formation of qi-deficiency syndrome in HFpEF patient.The correlation analysis between qi-deficiency syndrome and echocardiography indicators showed that the maximum speed(e')of the early dilation of the mitral annulus side was lower in qi-deficiency severe group than that in qi-deficiency slight group and control group(4.37 vs. 4.88 vs. 5.54，P=0.041，P=0.000)，and the early peak systolic velocity of mitral orifice dilation(E)/e' was highest(22.74 vs. 18.09 vs. 11.96，P=0.012，P=0.000)in qi-deficiency severe group.Conclusion:HFpEF qi-deficiency syndrome is associated with the distribution of comorbidities and impaired diastolic function. |
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