| 引用本文:樊俊1，王馨璐1，彭波2.半夏厚朴汤加减治疗老年肺心病急性加重期合并胃肠道功能障碍[J].世界中医药,2021,(08):. |
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| 半夏厚朴汤加减治疗老年肺心病急性加重期合并胃肠道功能障碍 |
| Effect of Modified Banxia Houpo Decoction on Senile Pulmonary Heart Disease in the Acute Exacerbation Period with Gastrointestinal Dysfunction |
| 投稿时间：2020-01-18 |
| DOI：10.3969/j.issn.1673-7202.2021.08.017 |
| 中文关键词: 半夏厚朴汤加减 老年肺心病急性加重期 胃肠道功能障碍 肺功能 胃肠动力 中医证候积分 生命质量 血生化指标 |
| English Keywords:Modified Banxia Houpo Decoction Elderly patients with pulmonary heart disease in the acute exacerbation period Gastrointestinal dysfunction Pulmonary function Gastrointestinal motility Traditional Chinese Medicine syndrome integral Quality of life Blood biochemical indexes |
| 基金项目:中医药传承与创新“百千万”人才工程：全国老中医药专家学术经验继承项目（国中医药人教发［2017］29号） |
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| 中文摘要: |
| 目的：观察半夏厚朴汤加减对老年肺心病急性加重期合并胃肠道功能障碍患者胃肠功能及肺功能的影响。方法：选取2018年1月至2019年1月上海市中医医院收治的老年肺心病急性加重期合并胃肠道功能障碍患者82例作为研究对象，按照随机数字表法分为观察组和对照组，每组41例。对照组予以常规临床治疗，观察组在对照组基础上加用半夏厚朴汤加减，每日1剂，均治疗2周。比较治疗前后2组患者的中医证候积分、生命质量评分、肺功能指标、超声胃排空指标及血生化指标的变化，统计不良反应发生情况。结果：治疗后2组中医证候积分和CAT评分、胃窦收缩频率及血生长抑素(SS)、二胺氧化酶(DAO)水平较治疗前明显降低（P<0.05），且观察组明显低于对照组（P<0.05）；治疗后2组FEV1/预测值、FEV1/FVC指标、胃半排空时间、胃窦收缩幅度、胃窦运动指数及血胃动素(MTL)水平均较治疗前明显升高（P<0.05），且观察组明显高于对照组（P<0.05）；2组治疗期间均未出现严重不良反应。结论：半夏厚朴汤加减能够改善老年肺心病急性加重期合并胃肠道功能障碍患者肺功能，提高胃肠动力，有助于缓解患者症状，促进疾病的康复。 |
| English Summary: |
| To observe the effect of modified Banxia Houpo Decoction on gastrointestinal function and pulmonary function in elderly patients with pulmonary heart disease in the acute exacerbation period and gastrointestinal dysfunction.Methods:A total of 82 elderly patients with acute exacerbation and pulmonale and gastrointestinal dysfunction were divided into an observation group and a control group according to the method of random number table，with 41 cases in each group.The control group was given routine clinical treatment.The observation group was treated with modified Banxia Houpo Decoction on the basis of the control group.After treating 2 weeks，the changes of TCM syndrome scores，quality of life scores，lung function index，gastric emptying index and blood biochemical index of the 2 groups before and after treatment were compared，and adverse reactions were recorded.Results:After treatment，the scores of TCM syndromes，the frequency of gastric antrum contraction，the level of blood SS and DAO in the 2 groups were significantly lower than those before treatment(P<0.05)，which in the observation group were significantly lower than those in the control group(P<0.05); the index of FEV1/predictive value，FEV1/FVC，gastric half emptying time，the amplitude of gastric antrum contraction，the index of gastric antrum movement and the level of blood MTL in the 2 groups were significantly higher than those before treatment(P<0.05)，which in the observation group were significantly higher than those in the control group(P<0.05).No serious adverse reactions occurred in the 2 groups during the treatment.Conclusion:The application of modified Banxia Houpu Decoction can improve the lung function and gastrointestinal motility of the elderly patients with pulmonary heart disease in the acute exacerbation period and gastrointestinal dysfunction，which is helpful to alleviate the symptoms and promote the recovery of the disease. |
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