| 引用本文:连雅君1,吴梦瑶2,赵德智3,张淑静1,孙晓光1.中药灌肠治疗放射性肠炎的系统评价[J].世界中医药,2021,(16):. |
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| 中药灌肠治疗放射性肠炎的系统评价 |
| Systematic Evaluation of Chinese Medicine Enema in the Treatment of Radiation Enteritis |
| 投稿时间：2020-07-06 |
| DOI：10.3969/j.issn.1673-7202.2021.16.013 |
| 中文关键词: 中药灌肠 放射性肠炎 放射性结肠炎 放射性直肠炎 放射性小肠炎 随机对照 Meta分析 系统评价 |
| English Keywords:Enema of traditional Chinese medicine Radiation enteritis Radiation rectitis Radiation enteritis Radiation colitis Randomized controlled trial META Systematic review |
| 基金项目:北京中医药薪火传承“3+3”工程（2020-SZ-C-80）——彭建中名医传承工作项目 |
| 作者 | 单位 | | 连雅君1,吴梦瑶2,赵德智3,张淑静1,孙晓光1 | 1 北京中医药大学中医学院,北京,100029
2 中国人民解放军301总医院,北京,100039
3 南京医科大学附属儿童医院,南京,210008 |
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| 中文摘要: |
| 目的：探究中药灌肠对放射性肠炎治疗的可能益处和风险。方法：检索中文中国期刊全文数据库、中国学术期刊数据库、中文科技期刊数据库、中国生物医学文献服务系统，英文数据库包括PubMed、Cochrane Central Register of Controlled Trials、EMBASE via OVID，检索时间从建库至2020年3月。使用Cochrane risk of bias工具评价研究的方法学质量，使用Revman 5.3软件对符合纳入标准的文章进行Meta分析。结果：共纳入50篇文献，40篇中药灌肠组与西药灌肠组比较，10篇中药结合西药灌肠组与西药灌肠组比较，共涉及1 396例患者。Meta分析结果显示：在有效率方面，中药灌肠组优于对照组（中药灌肠对比西药灌肠，RR=1.28，95%CI为1.23～1.32；中药结合西药灌肠对比西药灌肠，RR=1.28，95%CI为1.2～1.37）。在Karnofsky积分方面，中药灌肠组优于对照组（中药灌肠对比西药灌肠，RR=6.63，95%CI为2.81～10.45；中药结合西药灌肠对比西药灌肠，RR=4.92，95%CI为3.69～6.14）。结论：中药灌肠及中西药结合灌肠在缓解和治疗放射性肠炎方面，较西医灌肠治疗可能更有优势。但由于纳入文献质量不高，所获得结论的可靠性低。 |
| English Summary: |
| To explore the possible benefits and risks of traditional Chinese medicine enema in the treatment of radiation enteritis.Methods:Relevant literature on Chinese medicine enema treatment of radiation enteritis in Chinese and English databases were retrieved，Cochrane risk of bias tool was used to evaluate the methodological quality of the study，and Revman 5.3 software was used to perform meta-analysis on papers that met the inclusion criteria.Results:A total of 50 papers were included.As for 40 papers of Chinese medicine enema treatment groups，comparing with Western medicine enema group，10 papers involving Chinese medicine enema combined with Western medicine enema were compared with Western medicine enema group，involving a total of 1396 patients.Meta analysis results showed that：in the efficiency of Chinese medicine enema，the treatment group was better than the control group(Chinese medicine enema control Western medicine enema control type，RR=1.28，95%CI=1.23，1.32; Chinese medicine combined with Western medicine enema control Western medicine enema type.RR=1.28，95%CI=1.2，1.37).In terms of Karnofsky score of traditional Chinese medicine，the treatment group was better than the control group(Chinese medicine enema control Western medicine enema treatment control type，RR=6.63，95%CI=2.81，10.45); Chinese medicine combined with Western medicine enema control Western medicine enema control type，RR=4.92，95%CI=3.69，6.14).Conclusion:Chinese medicine enema and Chinese and Western medicine combined enema may have an advantage over Western medicine enema in relieving and treating radiation enteritis.However，because the quality of the included literature is not high，the reliability of the conclusions obtained is low. |
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