| 引用本文:唐魁韩1，陈龙2，刘平举3，李翔翮2，孔令超2，卢小龙1，孙立2.中医药基于核因子κB信号通路调控破骨细胞分化的研究进展[J].世界中医药,2022,(04):. |
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| 中医药基于核因子κB信号通路调控破骨细胞分化的研究进展 |
| Research Progress of Regulation of Osteoclast Differentiation |
| 投稿时间：2020-08-18 |
| DOI：10.3969/j.issn.1673-7202.2022.04.023 |
| 中文关键词: 中医药 核因子κB 信号通路 破骨细胞 研究进展 |
| English Keywords:Traditional Chinese medicine NF-κB Signaling pathway Osteoclast Research progress |
| 基金项目:贵州省中医药管理局中医药、民族医药科学技术课题研究资助项目(QZYY-2020-029) |
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| 中文摘要: |
| 中医药治疗骨相关疾病疗效显著,其分子生物学机制研究也成为热点,破骨细胞分化异常导致一系列骨相关疾病发生,中医药通过核因子κB(NF-κB)信号通路调控破骨细胞分化的研究取得不少进展。本文对中医药基于NF-κB信号通路的调控破骨细胞分化的研究现状进行归纳总结,阐明分子生物学机制,指出目前研究不足及未来研究方向,为中医药治疗骨相关疾病拓展思维。 |
| English Summary: |
| Traditional Chinese medicine(TCM)is effective in the treatment of bone-related diseases，and its molecular biological mechanism has become a hotspot.The abnormal differentiation of osteoclasts leads to a series of bone-related diseases.Research on the regulation of osteoclast differentiation through NF-κB signaling pathway in TCM has made a lot of progress.This paper summarizes the research status of the regulation of osteoclast differentiation based on the NF-κB signaling pathway in traditional Chinese medicine，elaborates the molecular biological mechanism，points out the current research deficiencies and future research directions，and expands the thinking for the treatment of bone-related diseases in TCM. |
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