| Tumor inflammatory microenvironment is composed of inflammatory cells,tumor cells,and stromal cells accompanied by infiltration of a large number of cytokines and chemokines,and plays a key role in tumor cell proliferation,invasion,angiogenesis,and chemoradiotherapy resistance.Its pathogenesis is characterized by internal accumulation of pathogenic heat,stagnant phlegm and fluid retention,blood stasis,and deficiency of vital qi,which are the embodiment of traditional Chinese medicine(TCM) syndrome at the micro-level.In terms of the abnormal inflammatory microenvironment,treatment based on syndrome differentiation should follow the therapeutic principles of clearing heat,removing toxins,resolving phlegm,dissipating mass,promoting blood circulation,removing blood stasis,reinforcing healthy qi,and consolidating body resistance,displaying a good anti-tumor prospect in relieving the clinical symptoms and regulating the immunity of the body. |
