世界中医药
文章摘要
引用本文:张玉雯1,王佳佳1,巴寅颖1,王文娟1,迟莉1,游超瑞2,王天芳2.中医药调节溃疡性结肠炎常见证候肠道菌群的研究进展[J].世界中医药,2022,(20):.  
中医药调节溃疡性结肠炎常见证候肠道菌群的研究进展
Research Progress on Traditional Chinese Medicine in Regulating Intestinal Flora in Ulcerative Colitis of Common Syndromes
投稿时间:2021-10-26  
DOI:10.3969/j.issn.1673-7202.2022.20.023
中文关键词:  溃疡性结肠炎  肠道菌群  辨证论治  证候  中医药  肠道菌群失调  机制  炎症性肠病
English Keywords:Ulcerative Colitis  Intestinal Flora  Syndrome Differentiation and Treatment  Syndromes  Traditional Chinese Medicine  Intestinal Flora Imbalance  Mechanism  Inflammatory Bowel Disease
基金项目:国家自然科学基金青年科学基金项目(82104765,81703670);北京市中医药“薪火传承3+3工程”冯建春名医传承工作站(2015-SZ-C-58)
作者单位
张玉雯1,王佳佳1,巴寅颖1,王文娟1,迟莉1,游超瑞2,王天芳2 1 首都医科大学中医药学院北京100069 2 北京中医药大学中医学院北京100029 
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中文摘要:
      溃疡性结肠炎作为难治性肠道疾病之一,其病因尚未完全明确,研究证实肠道菌群失调与溃疡性结肠炎发病联系密切。中医药治疗溃疡性结肠炎体现了整体调节、辨证论治的特色与优势,中医药可通过改善菌群结构、调节菌群数量、调整肠道菌群稳态治疗溃疡性结肠炎,且溃疡性结肠炎不同中医证候的肠道菌群存在着明显差异。现通过分析溃疡性结肠炎常见证候(大肠湿热证、脾虚湿蕴证、脾肾阳虚证、脾气亏虚证、肝郁脾虚证、寒热错杂证、热毒炽盛证)肠道菌群的特点及中医药调节溃疡性结肠炎常见证候肠道菌群的研究现状,以期为溃疡性结肠炎的微观辨证及中医药治疗溃疡性结肠炎的作用机制研究提供依据。
English Summary:
      The etiology of ulcerative colitis(UC),as one of the refractory intestinal diseases,has not been fully illustrated.However,it has been confirmed that the imbalance of intestinal flora is closely related to UC.Traditional Chinese medicine(TCM) in the treatment of UC reflects the characteristics and advantages of overall regulation and treatment based on syndrome differentiation.UC can be treated by TCM by improving the structure,regulating the number,and recovering the homeostasis of intestinal flora.In addition,there are certain differences in intestinal flora in the context of UC of different TCM syndromes.The present study analyzed the characteristics of intestinal flora in UC of common TCM syndromes(dampness-heat in large intestine syndrome,spleen deficiency with dampness accumulation syndrome,yang deficiency in spleen and kidney syndrome,spleen qi deficiency syndrome,liver qi stagnation and spleen deficiency syndrome,intermingled heat and cold syndrome,and blazing heat-toxin syndrome) and reviewed the research progress on TCM in regulating intestinal flora in UC,aiming to provide a basis for the microscopic syndrome differentiation of UC and the mechanism research of TCM in the treatment of UC.
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