| 引用本文:刘雪妍1，黄剑2，姚昊1，杨艳蓉1，郑入文2.针灸对结直肠癌术后胃肠功能恢复作用的系统评价[J].世界中医药,2023,(04):. |
|
| 针灸对结直肠癌术后胃肠功能恢复作用的系统评价 |
| Effect of Acupuncture and Moxibustion on the Recovery of Postoperative Gastrointestinal Function of Colorectal Cancer：A Meta-analysis |
| 投稿时间：2021-06-16 |
| DOI：10.3969/j.issn.1673-7202.2023.04.006 |
| 中文关键词: 针灸 结直肠癌 术后 胃肠功能恢复 有效率 随机对照试验 系统评价 Meta分析 |
| English Keywords:Acupuncture and moxibustion Colorectal cancer Postoperation Recovery of gastrointestinal function Efficacy Randomized controlled trial Systematic review Meta-analysis |
| 基金项目:国家自然科学基金项目（81904287） |
|
| 摘要点击次数: 285 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的：系统评价针灸干预结直肠癌术后胃肠功能恢复的有效性。方法：检索国家知识基础设施数据库（CNKI）、中国学术期刊数据库（CSPD）、中文科技期刊数据库（CCD）、中国生物医学文献数据库（CBM）、PubMed、Embase、Cochrane Library数据库自建库至2021年5月关于针灸治疗对结直肠癌术后胃肠功能的恢复作用随机对照试验（RCT），由2名研究者独立对纳入文献进行质量评价及信息提取，再采用RevMan 5.3软件进行Meta分析。结果：最终纳入18篇文献，其中中文文献17篇，英文文献1篇，包括1 523例患者。Meta分析结果显示，与对照组比较，观察组对结直肠癌术后胃肠功能恢复的有效率更高，差异有统计学意义（RR=1.11，95%CI为1.02~1.21，P=0.02）；首次肛门排气时间更短，差异有统计学意义（SMD=-1.07，95%CI为-1.31~-0.83，P<0.000 01）；肠鸣音恢复时间更短，差异有统计学意义（MD=-8.40，95%CI为-10.23~-6.57，P<0.000 01）；首次肛门排便时间更短，差异有统计学意义（SMD=-1.06，95%CI为-1.32~-0.80，P<0.000 01），经敏感性和亚组分析未发现异质性来源。结论：在结直肠癌患者术后应用针灸治疗，可以有效促进术后胃肠功能的恢复，但由于此次纳入文献的证据质量等级不高，异质性较大，未来需要临床大样本，多中心，高质量的RCT进行进一步验证。 |
| English Summary: |
| To systematically evaluate the efficacy of acupuncture and moxibustion in the recovery of postoperative gastrointestinal function of colorectal cancer.Methods:China National Knowledge Infrastructure(CNKI)，China Science Periodical Database(CSPD)，Chinese Citation Database(CCD)，Chinese Biomedical Literature Database(CBM)，PubMed，Embase and Cochrane Library were searched to collect the randomized controlled trials(RCTs) on acupuncture and moxibustion in the treatment of postoperative gastrointestinal function of colorectal cancer from the inception of the databases to May 2021.Two researchers independently evaluated the quality of the included literature and extracted the data.Meta-analysis was performed by Revman 5.3.Results:Eighteen articles were included，with 17 Chinese articles and 1 English article，involving 1 523 patients.The Meta-analysis revealed that compared with the control group，the observation group had higher efficacy in the recovery of gastrointestinal function(RR=1.11，95%CI 1.02 to 1.21，P=0.02)，shorter time of first anal exhaust(SMD=-1.07，95%CI -1.31 to -0.83，P<0.000 01)，shorter recovery time of bowel sounds(MD=-8.40，95%CI -10.23 to -6.57，P<0.000 01)，and shorter time of first defecation(SMD=-1.06，95%CI -1.32 to -0.80，P<0.000 01).The source of heterogeneity was not found by sensitivity and subgroup analysis.Conclusion:Acupuncture and moxibustion can effectively promote the recovery of gastrointestinal function of patients with colorectal cancer after operation.However，due to the low quality and large heterogeneity of the included literature，large-scale，multi-center and high-quality RCTs are needed for further verification. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
