| 引用本文:陈少裕1，戴璇1，陈鹏1，张梦颖1，李京心1，孙燕妮2.五虎汤药理作用及临床应用研究进展[J].世界中医药,2023,(19):. |
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| 五虎汤药理作用及临床应用研究进展 |
| Pharmacological Action and Clinical Application of Wuhu Decoction：A Review |
| 投稿时间：2022-09-03 |
| DOI：10.3969/j.issn.1673-7202.2023.19.026 |
| 中文关键词: 五虎汤 呼吸系统 肺炎 哮喘 痰热壅肺 药理作用 临床疗效 研究进展 |
| English Keywords:Wuhu Decoction Respiratory system Pneumonia Asthma Phlegm-heat obstructing lung Pharmacological effects Clinical efficacy Research progress |
| 基金项目:国家自然科学基金项目（81573901）；上海市普陀区中心医院院内课题（2020311B） |
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| 中文摘要: |
| 五虎汤首载于《仁斋直指方》，具有清热化痰、宣肺平喘等功效，历代医家应用五虎汤治疗痰哮、风寒、马脾风等病症。系统检索国家知识基础设施数据库（CNKI），中国学术期刊数据库（CSPD）等数据库近年来公开发表的关于五虎汤的临床应用及相关的药效机制研究文献，总结发现五虎汤具有抗炎、降低气道反应性，抑制气道重塑、舒张支气管平滑肌、降低气道黏液储备和胶原沉积指数、重建免疫平衡、抗病毒等功效，现临床上常用于治疗肺炎、流感、支气管哮喘等疾病，疗效显著。现对五虎汤治疗呼吸系统相关疾病的一系列研究及临床运用进行整理和分析总结，以期为今后五虎汤在临床得到更深入的研究与广泛的运用。 |
| English Summary: |
| Wuhu Decoction，first published in Ren-Zhai's Straight Directions of Prescriptions(Ren Zhai Zhi Zhi Fang)，has the effects of clearing heat，reducing phlegm，ventilating lung and relieving asthma.Physicians of all dynasties used Wuhu Decoction to treat asthma due to much phlegm，wind cold，infantile acute asthma and other diseases.This paper systematically searched the literature on the clinical application and relevant pharmacodynamic action of Wuhu Decoction published in China National Knowledge Infrastructure(CNKI)，Wanfang Data，and other databases in recent years.It concluded that Wuhu Decoction exerts anti-inflammatory and antiviral effect，reduces airway responsiveness，inhibits airway remodeling，relaxes bronchial smooth muscle，lowers airway mucus reserve and collagen deposition index，and rebuilds immune balance.Nowadays，the prescription is usually used to treat pneumonia，influenza，bronchial asthma and other diseases，with significant efficacy.On this basis，this paper sorted out and analyzed the research and clinical application of Wuhu Decoction in the treatment of respiratory diseases，aiming to facilitate the in-depth and extensive clinical application of Wuhu Decoction in the future. |
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