| 引用本文:李志更1，刘林2，马培3，张宁2，周宇馨2，刘阳2，岳利峰2，卫景沛2，康庆2.艾灸联合钙尔奇D治疗原发性骨质疏松的疗效评估[J].世界中医药,2023,(20):. |
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| 艾灸联合钙尔奇D治疗原发性骨质疏松的疗效评估 |
| Therapeutic Effect of Moxibustion in Combination with Caltrate D on Primary Osteoporosis |
| 投稿时间：2022-02-07 |
| DOI：10.3969/j.issn.1673-7202.2023.20.018 |
| 中文关键词: 艾灸 钙尔奇D 原发性骨质疏松 疗效评估 |
| English Keywords:Moxibustion Caltrate D Primary osteoporosis Evaluation of therapeutic effect |
| 基金项目:国家自然科学基金项目（81302960，82174046）；北京中医药大学杰出青年人才项目和青年名医培育项目（BUCM-2019-JCRC007，BUCM-2019-QNMYB011）;中国医学科学院医学与健康科技创新工程项目（2021-I2M-1-031） |
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| 中文摘要: |
| 目的：评估艾灸联合钙尔奇D治疗原发性骨质疏松的疗效。方法：回顾性选取2016年9月至2019年9月期间诊疗的120例原发性骨质疏松的患者，将其随机分为对照组和艾灸组，对照组采用钙尔奇D治疗，艾灸组在同等剂量钙尔奇D治疗的基础上，增加艾灸治疗，治疗周期为6个月。对比2组治疗前后的疼痛积分（VAS）、骨密度（BMD）、25羟基维生素D3、Ⅰ型胶原交联C端肽(β-CTX)、甲状旁腺激素（PTH）指标变化和治疗有效率等方面进行疗效评估。结果：治疗后，与对照组比较，艾灸组能明显缓解骨质疏松症状、骨性疼痛，影像提示艾灸组更有效改善患者的BMD，骨代谢相关的3项指标均明显改善，各方面均有统计学意义(均P<0.01)。结论：艾灸联合钙尔奇D治疗原发性骨质疏松后，症状缓解，疗效提升，且未出现明显不良反应。 |
| English Summary: |
| To evaluate the therapeutic effect of moxibustion in combination with Caltrate D on primary osteoporosis.Methods:A total of 120 patients with primary osteoporosis treated from September 2016 to September 2019 were randomizd into a control group and a moxibustion group.The control group was treated with Caltrate D，and the moxibustion group with moxibustion in combination with Caltrate D.Both groups were treated for 6 months.The visual analogue scale(VAS) score，bone mineral density(BMD)，25 hydroxy vitamin D3 [25(OH)D3]，beta-C-terminal telopeptide(β-CTX)，and parathyroid hormone(PTH) were determined before and after treatment，and the response rate was compared between the two groups.Results:Compared with the control group，moxibustion alleviated the symptoms and bone pain of osteoporosis.The moxibustion group outperformed the control group in improving the BMD and the 3 bone metabolism indicators(P<0.01).Conclusion:Moxibustion in combination with Caltrate D can relieve the symptoms and demonstrate improve effect on primary osteoporosis without causing obvious adverse reactions. |
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