| 引用本文:李世永1，高希言1，2，李胜男1，高崚1，2，吴琼1，褚文明1，曹原1.针灸联合补肾祛风湿中药治疗老年类风湿性关节炎的临床观察[J].世界中医药,2023,(20):. |
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| 针灸联合补肾祛风湿中药治疗老年类风湿性关节炎的临床观察 |
| Clinical Observation of Acupuncture and Moxibustion Combined with Traditional Chinese Medicine for Tonifying Kidney and Dispelling Wind-dampness in the Treatment of Elderly-onset Rheumatoid Arthritis |
| 投稿时间：2023-03-29 |
| DOI：10.3969/j.issn.1673-7202.2023.20.019 |
| 中文关键词: 针灸 补肾祛风湿 中药 老年 类风湿性关节炎 炎症介质 风湿因子 临床疗效 |
| English Keywords:Acupuncture and moxibustion Tonifying kidney and dispelling wind-dampness Traditional Chinese medicine Elderly Rheumatoid arthritis Inflammatory mediators Rheumatic factors Clinical efficacy |
| 基金项目:河南省中医药科学研究专项（2022ZY1097） |
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| 中文摘要: |
| 目的：探讨针灸联合补肾祛风湿中药对老年类风湿性关节炎（RA）的临床疗效。方法：选取2020年2月至2022年10月河南中医药大学第三附属医院收治的RA患者97例进行回顾性分析，按照不同的治疗方法分为对照组（n=48）和观察组（n=49）。对照组患者给予甲氨蝶呤片治疗，观察组患者给予针灸联合补肾祛风湿中药治疗，2个月后，比较2组患者临床疗效、炎症介质、临床症状、风湿因子和不良反应。结果：观察组治疗后总有效率为95.92%，高于对照组的79.17%（P<0.05），炎症介质[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、C反应蛋白(CRP)]，风湿因子[红细胞沉降率(ESR)、类风湿因子(RF)、免疫球蛋白G(IgG)]水平均低于对照组（P<0.05）。2组患者治疗后各临床症状均明显改善，且观察组优于对照组（P<0.05）。观察组不良反应发生率为20.41%，对照组为18.75%，差异无统计学意义（P>0.05）。结论：针灸联合补肾祛风湿中药对老年RA患者临床疗效显著，可有效抑制机体炎症反应，延缓病情进展，改善临床症状，且安全性良好。 |
| English Summary: |
| To explore the clinical effect of acupuncture and moxibustion combined with traditional Chinese medicine for tonifying kidney and removing wind-dampness on elderly-onset rheumatoid arthritis(RA).Methods:The clinical data of 97 RA patients admitted to the Third Affiliated Hospital of Henan University of Chinese Medicine from February 2020 to October 2022 were analyzed retrospectively.According to different treatment methods，the patients were divided into the control group(n=48) and the observation group(n=49).The control group received methotrexate tablets，while the observation group received acupuncture and moxibustion combined with traditional Chinese medicin for tonifying kidney and dispelling wind-dampness.After the treatment for two months，the clinical efficacy，inflammatory mediators，clinical symptoms，rheumatic factors and adverse reactions were compared between the two groups.Results:The total effective rate of the observation group after treatment was 95.92%，higher than the 79.17% of the control group(P<0.05).After treatment，the inflammatory mediators[tumor necrosis factor-α(TNF-α)，interleukin-6(IL-6)，C-reactive protein(CRP)]，rheumatoid factors[erythrocyte sedimentation rate(ESR)，rheumatoid factor(RF)，immunoglobulin G(IgG)] levels were all lower in the observation group than in the control group(P<0.05).After treatment，the clinical symptoms in both groups were significantly improved，with the observation group showing better results than the control group(P<0.05).The incidence of adverse reactions in the observation group was 20.41%，while in the control group，it was 18.75%，with no statistically significant difference between the groups(P>0.05).Conclusion:Acupuncture and moxibustion combined with traditional Chinese medicine for tonifying kidney and removing wind-dampness has a significant clinical effect on elderly-onset RA patients，which can inhibit the inflammatory reaction of the body，delay disease progression，improve the clinical symptoms，and have good safety. |
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