| 引用本文:黎征鹏1，章晓云1，2，曾浩1，高振罡1.基于“脏腑-骨痿”理论探讨绝经后骨质疏松症的发病机制[J].世界中医药,2024,(19):. |
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| 基于“脏腑-骨痿”理论探讨绝经后骨质疏松症的发病机制 |
| Pathogenesis of Postmenopausal Osteoporosis Based on “Internal Organ-bone Flaccidity” Theory |
| 投稿时间：2024-01-03 |
| DOI：10.3969/j.issn.1673-7202.2024.19.021 |
| 中文关键词: 绝经后骨质疏松症 脏腑 中医理论 发病机制 气血 津液 气机 气机升降 |
| English Keywords:Postmenopausal osteoporosis Internal organs Traditional Chinese medicine theory Pathogenesis Qi and blood Body fluid Qi movement Ascending and descending of qi movement |
| 基金项目:国家自然科学基金项目（82360937）；广西自然科学基金面上项目（2023GXNSFAA026075）；广西中医药适宜技术开发与推广项目（GZSY22-36）；广西中医药多学科交叉创新团队项目（GZKJ2310）；黄有荣桂派中医大师培养项目（桂中医药科教发〔2022〕6号）；广西中医药大学青年创新研究团队项目（2021TD001） |
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| 中文摘要: |
| 绝经后骨质疏松症（PMOP）是一种常见的骨骼疾病，属于高转换型的骨质疏松症(OP)，好发于女性绝经后5~10年。由于绝经后女性卵巢衰退，雌性激素和相关激素水平紊乱，进而引起骨量减少和骨微观结构发生改变，骨脆弱增加，患者骨折风险增加。中医学认为，肾虚是本病发生的关键，肾精充足对于骨髓充养和骨密度的提高起着至关重要的作用。同时，肝主疏泄，脾主运化，肺主行气，心血亏虚、胆气不足、肠道功能紊乱等因素同样影响骨的生长。 |
| English Summary: |
| Postmenopausal osteoporosis(PMOP) is a common skeletal disorder classified as high-turnover osteoporosis(OP)，most prevalent in women 5 to 10 years after menopause.The condition arises from ovarian decline in postmenopausal women，leading to disruptions in estrogen and related hormone levels，which result in reduced bone mass，altered bone microarchitecture，increased bone fragility，and a heightened risk of fractures.In traditional Chinese medicine(TCM)，kidney deficiency is considered a key factor in the development of this condition.Adequate kidney essence plays a crucial role in nourishing bone marrow and improving bone density.Additionally，the liver's function in regulating the smooth flow of qi，the spleen's role in transportation and transformation，and the lung's regulation of qi circulation are all vital.Other factors，such as heart blood deficiency，insufficient gallbladder qi，and intestinal dysfunction，also influence bone growth and health. |
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