引用本文:邹慕菡,吴灏,胡双飞,钟梦丽,苏薇薇,李沛波.化橘红化学成分、药理作用及毒理学研究进展[J].世界中医药,2024,(24):. |
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化橘红化学成分、药理作用及毒理学研究进展 |
Research Progress on Chemical Components,Pharmacological Effects,and Toxicology of Citri Grandis Exocarpium |
投稿时间:2024-04-03 |
DOI:10.3969/j.issn.1673-7202.2024.24.023 |
中文关键词: 化橘红 化学成分 药理作用 毒理学研究 作用机制 开发利用 研究进展 综述 |
English Keywords:Citri Grandis Exocarpium Chemical components Pharmacological effects Toxicological research Mechanism of action Development and utilization Research progress Review |
基金项目:国家自然科学基金面上项目(82004043);广东省自然科学基金面上项目(2023A1515011953);岭南现代农业科学与技术广东省实验室茂名分中心基金资助课题(2022ZD006) |
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中文摘要: |
化橘红化学成分主要包括黄酮类化合物、挥发油、多糖、香豆素类化合物、无机元素和肌醇等。现代药理学研究表明,化橘红及其化学成分具有止咳、祛痰、平喘、降血糖、降血脂、抗癌、抗病毒、抗肝损伤、抗心肌损伤、抗肺纤维化、抗肺动脉高压、神经保护、抗血栓、抗氧化、抗炎、免疫调节等药理活性。毒理学研究证实其安全性良好。 |
English Summary: |
The chemical composition of Citri Grandis Exocarpium mainly includes flavonoids,volatile oils,polysaccharides,coumarin compounds,inorganic elements,and inositol.Modern pharmacological studies have shown that Citri Grandis Exocarpium and its chemical components possess a variety of pharmacological activities,including antitussive,expectorant,antiasthmatic,hypoglycemic,hypolipidemic,anticancer,antiviral,hepatoprotective,cardioprotective,anti-pulmonary fibrosis,anti-pulmonary hypertension,neuroprotective,antithrombotic,antioxidant,anti-inflammatory,and immunomodulatory effects.Toxicological studies have confirmed its good safety profile. |
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