To observe Clinical curative effect of Zhigan Heji for the treatment of fatty liver due to combined phlegm and blood stasis.Methods:60 cases of fatty liver due to combined phlegm and blood stasis were randomly divided into treatment group(30 cases,treated by Zhigan Heji) and control group (30 cases,treated by Diisopropylamine).The course of treatment lasted for three months.The clinical symptoms,physical signs,liver function,blood fat and type B ultrasonic of liver,etc. of the patients were observed.Results:The total effective rate of the treatment group was 93.33%,while that of the control group was 83.33%.Besides,Zhigan Heji is better than Diisopropylamine in improving clinical symptoms and physical symptoms,repairing liver function and relieving hepatitis(P<0.05),but their curative effect on reducing blood fat didn’t show significant difference(P>0.05).Conclusion:Zhigan Heji is an effective medicine for treatment of fatty liver due to combined phlegm and blood stasis.