As far as therapeutic principles for treating chronic renal failure(CRF) with Chinese medicine are concerned,syndrome differentiation and treatment,integrated therapy,balancing deficiency and excess as well as degree of urgency should be emphasized;Syndrome differentiation should focus on five zang organs,i.e.heart,liver,spleen,lung and kidney;Precaution for CRF should include treating disease before its onset,preventing external contraction,avoiding overstrain,keeping away from herbal toxicity,etc.