To explore functions and possible mechanism of a Chinese medical prescription-Kechuanning and provide evidences for treatment of asthma. 〖WTHZ〗Methods: 60 mice were randomly divided into 6 groups, all of which were given 0.2mg/ml antigen solution at 1, 7, 14 day, except for the normal control group, then inhaled 0.05% egg albumin by ultrasonic atomization for 14 consecutive days. The normal control group was given sodium chloride everyday. Treatment groups were treated respectively with 0.0617mg/ml Corson, 98.7mg/ml、197.4mg/ml、394.8mg/ml Kechuanning. Immuno-histrochemical staining method was used to compare levels of TGF-β in BALF. Results: level of TGF-β in BALF rose remarkably as compared to that of the normal control group. Conclusion: The result suggested that Kechuanning's performed its functions through inhibition of production of TGF-β.