Malignant tumors are a result of accumulative toxin. Therefore, toxin, as the main etiological factor, should be given full consideration when it comes to prevention and cure of malignant tumors. Evil toxin take many forms, such as toxin of hot (‘fire’), damp, dry and ‘yin’, among which toxin of hot is most common. Applying three therapies at right moment, i.e. countering toxin substances, expelling of toxin and deintoxication are proven to be effective for clinical treatment of tumors. Those therapies must be used boldly and cautiously. Please note that toxin should be expelled to the very limit by all means, while treatment should be discontinued as such satisfactory results have been achieved, avoiding over treatment or mistreatment.