Abstract:to treat Impaired Glucose Tolerance (IGT) with the Chinese medical method of spleen fortifying and liver soothing to reduce risk of conversion to diabetes.Methods:Confirmed IGT subjects were randomly grouped to the lifestyle intervention group (22 cases), the integrative group (take Spleen Fortifying and Blood Reduction Granules orally plus deltamine, 24 cases), and the biomedicine group (with deltamine, 20 cases). All subjects were intervened in life style. After one period of treatment (3 months), blood sugar and blood fat of respective groups were observed.Results:FPG and 2hPG levels of all groups were lowered (P<0.05~0.001) after treatment, and the tendency were more significant of the integrative group and biomedicine group (P<0.001). Drop of TG and TC levels were inconspicuous of the intervention group (P<0.1), but marked of the integrative group (P<0.05~P<0.001). TG level dropped mildly (P<0.1), while TC level was significantly down (P<0.05) of the biomedicine group.Conclusion:life style intervention, Spleen Fortifying and Blood Reduction Granules and deltamine can lower BS level of IGT patients. In particular the granule was able to improve levels of fasting plasma glucose, postprandial blood sugar and blood fat in the way to effectively cure IGT disease.