to explore the action mechanism of Arthritis Pill for rheumatoid arthritis.Methods:Impact of the pill on TNF-α and IL-1β was observed on plasma of rats with adjuvant arthritis, and compared with positive control group which were treated with Tripterygii wilfordii Radix.Results:The pill was superior to the control medicinal in suppressing TNF-α and IL-1β of inflammatory tissue.Conclusion:Immunity Enhancement, anti-inflammatory and anti-rheumatism action of the Arthritis pill acts on arresting releasing of inflammatory mediators.