To study pharmacodynamics of the expectorant and antitussive effects of Wanbei Anti-cough Capsule.Methods:Ammomia and electronic stimuli acted respectively in mice and at cats' superior laryngeal nerve to induce cough. Phenolsulfonphthalein Test in mice and capillary method in rats were used in expectorant test.Results:Various doses of Wanbei Capsule had obvious antitussive effects in rats and cats. In expectorant test, Wanbei Capsule made fascinating expectorant effects in rats and mice with a significant difference with that of the model control groups (P<0.05 or P<0.01). Conclusions:Showing a relatively strong expectorant and antitussive effect, Wanbei Anti-cough Capsule had better curative effect than the positive control medicine-bromhexine hydrochloride and is advisory for application.