to observe effectiveness of integrative Chinese and western medicine for systemic lupus erythematosus (SLE).Methods:the control group was treated with hormones; in addition to hormone treatment, the treat group was differentiated in terms of its Chinese medical syndromes (in this case, there were 3 types of syndromes) and treated accordingly.Results:of 60 cases in the treat group, the total effective rate was 91.7%: twenty-nine people’s symptoms were relieved, 18 people were very effective, 8 people were effective, and 5 people failed to respond, compared with the total effective rate of 80% for 50 cases of the control group: eleven people’s symptoms were relieved, 10 people were very effective, 19 people were effective, and 10 people failed to respond. There were significant differences between two groups (P<0.01).Conclusion:Integrative Chinese and western medicine has satisfactory effect on SLE.